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Special Issue "Reverse Vaccinology and Vaccine Antigens"
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Attenuated/Inactivated/Live and Vectored Vaccines".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 11951
Special Issue Editor
Interests: porcine; chicken and fish vaccinology; identification of novel vaccine antigens; reverse vaccinology; antibody repertoire; DNA vaccination; mucosal vaccination
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
It is not always possible to identify vaccine antigens by classical strategies. Therefore, novel identification strategies based, at least partly, on bioinformatic analyses have been developed over the last years. For example, reverse vaccinology consists in researching genes of the pathogen encoding potential vaccine antigens using specific software and databases. One other example is based on high throughout sequencing and analysis of the antibody repertoire of hosts after infection with a given pathogen. This could help to identify sequences of antibodies specifically involved in the protection against this pathogen, which will then make it possible to go back to the targeted epitope, again by bioinformatics analyses. Such strategies were first applied to develop novel human vaccines. Afterwards, similar strategies were employed in the veterinary field.
The aim of this specific issue is to publish papers describing the development or optimization of human or veterinary vaccines identified through reverse vaccinology or other strategies partly based on bioinformatics (for example after antibody repertoire analysis). This issue will also contains papers describing the development of novel bioinformatics strategies enabling the research of vaccine antigens or papers showing novel methods enabling the expression of antigens identified by bioinformatics strategies. This will include B and/or T-cell antigens.
Dr. Daniel Dory
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- novel reverse vaccinology tools
- antibodies sequencing
- human and veterinary vaccine antigens identified through bioinformatic based strategies
- B-cell antigen identification
- T-cell antigen identification
- bacteria, viral of parasite vaccine antigens
- antigen vectors
- antigen expression