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Point-of-Care Sensing Devices
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Point-of-Care Sensing Devices

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (30 November 2019) | Viewed by 11297

Special Issue Editors

Dr. Ajeet Kaushik

E-Mail Website
Guest Editor
Department of Natural Sciences, Division of Sciences, Arts & Mathematics (SAM), Florida Polytechnic University, Lakeland, FL 33805-8531, USA
Interests: functional materials; polymers; sensors; biosensors; nanomedicine drug delivery systems
Special Issues, Collections and Topics in MDPI journals
Dr. Mubarak Mujawar

E-Mail Website
Guest Editor
Department of Electrical and Computer Engineering, Florida International University, Miami, FL 33174, USA
Interests: IoT; wearable sensors and systems; micro/nanofabrication; MEMS; low-temperature plasma systems and diagnostics; physics and engineering education

Special Issue Information

Dear Colleagues,

The need for early-stage disease diagnostics to manage targeted diseases and determine timely therapeutics has raised the demand for smart advanced analytical diagnostics tools. Advancements in materials and electronics have enabled the development of efficient biosensors for the detection of biomarkers at desired levels and ranges. Such developed biosensors have served as potential analytical tools for real-time monitoring of bio-markers to generate the bio-informatics needed for disease monitoring and to understand the epidemic and progression under therapy to optimize timely treatment. The integration of biosensing platforms with micro-electronics and interfacing them with smartphones have made early-stage disease diagnostics possible at a point-of-care (POC) application. In spite of numerous advancements in smart biosensing, efforts are being continuously made to develop cost-effective next-generation biosensors with reduced form factors for better health wellness. 

Keeping the advancements, challenges, and future prospects in mind, this Special Issue of Sensors entitled "Point-of-Care Sensing Devices" focuses on fundamental and applied research in order to develop biosensors for POC application. This Special Issue invites mini reviews, reviews, letters, and research articles related to the field of nanotechnology, advanced functional sensing materials, numerical simulations, advancements in transduction, miniaturized sensing system development, and the internet of things (IoT). Technological advancement in signal amplification and developments in optical, electrical, magnetic, and physical sensing strategies to fabricate an efficient sensing system are also covered in this issue.

This Special Issue will serve as a guideline to scientists who are planning to conduct research in the area of designing and developing a miniaturized sensing system at POC application for personalized health care.

Dr. Ajeet Kaushik
Dr. Mubarak Mujawar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Advanced functional nanostructures 
  • Thin films 
  • Numerical simulation 
  • Advanced devices 
  • Sensing systems
  • Internet of things 
  • Biosensors
  • Miniaturized systems 
  • Wearable sensing systems
  • BioMEMS systems
  • Bioinformatics 
  • System for diseases diagnostics
  • Point-of-care devices/applications

Published Papers (3 papers)

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Editorial

Jump to: Research

4 pages, 5969 KiB  
Editorial
Point of Care Sensing Devices: Better Care for Everyone
by Ajeet Kaushik and Mubarak A. Mujawar
Sensors 2018, 18(12), 4303; https://doi.org/10.3390/s18124303 - 06 Dec 2018
Cited by 39 | Viewed by 4285
Abstract
Improved health management is a key to provide a better health care [...] Full article
(This article belongs to the Special Issue Point-of-Care Sensing Devices)
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Research

Jump to: Editorial

10 pages, 3850 KiB  
Article
Automatic Range Adjustment of the Fluorescence Immunochromatographic Assay Based on Image Processing
by Ruixin Jiang, Huihuang Wu, Jianpeng Yang, Haiyan Jiang, Min Du, Mangi Vai, Siohang Pun and Yueming Gao
Sensors 2020, 20(1), 209; https://doi.org/10.3390/s20010209 - 30 Dec 2019
Cited by 5 | Viewed by 2380
Abstract
As an emerging technology, fluorescence immunochromatographic assay (FICA) has the advantages of high sensitivity, strong stability and specificity, which is widely used in the fields of medical testing, food safety and environmental monitoring. The FICA reader based on image processing meets the needs [...] Read more.
As an emerging technology, fluorescence immunochromatographic assay (FICA) has the advantages of high sensitivity, strong stability and specificity, which is widely used in the fields of medical testing, food safety and environmental monitoring. The FICA reader based on image processing meets the needs of point-of-care testing because of its simple operation, portability and fast detection speed. However, the image gray level of common image sensors limits the detection range of the FICA reader, and high-precision image sensors are expensive, which is not conducive to the popularization of the instrument. In this paper, FICA strips’ image was collected using a common complementary metal oxide semiconductor (CMOS) image sensor and a range adjustment mechanism was established to automatically adjust the exposure time of the CMOS image sensor to achieve the effect of range expansion. The detection sensitivity showed a onefold increase, and the upper detection limit showed a twofold increase after the proposed method was implemented. In addition, in the experiments of linearity and accuracy, the fitting degree (R2) of the fitted curves both reached 0.999. Therefore, the automatic range adjustment method can obviously improve the detection range of the FICA reader based on image processing. Full article
(This article belongs to the Special Issue Point-of-Care Sensing Devices)
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13 pages, 4457 KiB  
Article
Design of a Portable Orthogonal Surface Acoustic Wave Sensor System for Simultaneous Sensing and Removal of Nonspecifically Bound Proteins
by Shuangming Li and Venkat R. Bhethanabotla
Sensors 2019, 19(18), 3876; https://doi.org/10.3390/s19183876 - 08 Sep 2019
Cited by 9 | Viewed by 3950
Abstract
One challenge for current surface acoustic wave (SAW) biosensors is reducing nonspecific adsorption. A device propagating Rayleigh and shear horizontal surface acoustic waves in orthogonal directions fabricated in ST quartz has the capability of achieving simultaneous detection and nonspecific binding (NSB) protein removal. [...] Read more.
One challenge for current surface acoustic wave (SAW) biosensors is reducing nonspecific adsorption. A device propagating Rayleigh and shear horizontal surface acoustic waves in orthogonal directions fabricated in ST quartz has the capability of achieving simultaneous detection and nonspecific binding (NSB) protein removal. Current measurement methods for a SAW sensor system based on this device require large-size and expensive equipment such as a vector network analyzer (VNA), signal generator, and frequency counter, which are not suitable for portable, especially point-of-care, applications. In this work, a portable platform based on a direct digital synthesizer (DDS) is investigated for the orthogonal SAW sensor, integrating signal synthesis, gain control, phase/amplitude measurement, and data processing in a small, portable electronic system. This prototype was verified for both stability and repeatability, and the results matched very well with VNA measurements. Finally, system performance in real-time sensing and NSB removal was evaluated. Full article
(This article belongs to the Special Issue Point-of-Care Sensing Devices)
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