Antimicrobials in Plants: From Traditional Medicine to Modern Therapeutic Agents

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Pharmaceutical Processes".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 2210

Special Issue Editors


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Guest Editor
Department of Pharmacognosy-Phytotherapy, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania
Interests: pharmacognosy; phytochemistry; high-resolution mass spectrometry; gas chromatography; antimicrobials; anticancer; anti-inflammatory
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Guest Editor
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland
Interests: microbiology; antimicrobial activity testing; biofilm; infectious diseases; microbiota; molecular microbiology; antibiotic resistance
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Infectious diseases are responsible for large-scale morbidity and mortality worldwide. The emergence of multi-drug-resistant pathogens represents one of the greatest challenges modern medicine needs to face. In this context, there is a high demand for greater research efforts to identify new antimicrobial strategies. Plant-based antimicrobials are valuable tools in the fight against pathogens due to their multi-componential nature, which translates into a multi-target activity and constitutes a great advantage compared to the single-target effects of conventional antimicrobials. In addition, synergistic interactions between plant extracts and antimicrobial drugs are promising approaches to improve their efficacy, decrease toxicity, and reverse microbial resistance. Moreover, plant metabolites have served as scaffolds for the synthesis and semi-synthesis of novel antimicrobial drugs.

Therefore, this Special Issue welcomes the submission of articles (both original research papers and reviews) that focus on the importance of phytochemicals as antimicrobial agents in human health, food and veterinary medicine, and look to highlight preclinical and clinical findings on plant-based antimicrobials.

Dr. Adriana Trifan
Dr. Izabela Korona-Głowniak
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant products
  • antimicrobial agents
  • antibiotic resistance
  • multi-drug resistance
  • preclinical (in vitro/in vivo) studies
  • clinical studies
  • evidence-based medicine
  • systematic reviews & meta-analyses

Published Papers (1 paper)

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Research

13 pages, 7368 KiB  
Article
Antimicrobial and Photocatalytic Activities of Selenium Nanoparticles Synthesized from Elaeagnus indica Leaf Extract
by Dhatchanamoorthi Indhira, Arumugam Aruna, Krishnamoorthy Manikandan, Mohammed F. Albeshr, Abdulwahed Fahad Alrefaei, Ramachandran Vinayagam, Arumugam Kathirvel, Selvaraj Ranjith Priyan, Govindan Suresh Kumar and Ramalingam Srinivasan
Processes 2023, 11(4), 1107; https://doi.org/10.3390/pr11041107 - 04 Apr 2023
Cited by 10 | Viewed by 1817
Abstract
Selenium nanoparticles (Se NPs) have recently received much interest due to their low toxicity, high bioavailability, and wide applications. This study synthesized Se NPs using selenious acid as a starting material and leaf extract from Elaeagnus indica as a reducing agent. Spectroscopic and [...] Read more.
Selenium nanoparticles (Se NPs) have recently received much interest due to their low toxicity, high bioavailability, and wide applications. This study synthesized Se NPs using selenious acid as a starting material and leaf extract from Elaeagnus indica as a reducing agent. Spectroscopic and electron microscopy investigations have demonstrated the production of aggregated amorphous Se NPs with phytochemicals. Furthermore, the reduction of selenious acid into Se NPs by phytochemicals present in the leaf extract of E. indica was confirmed in a prominent band at 269 nm in the UV-visible spectrum. The biosynthesized selenium nanoparticles have a 10–15 nm particle size distribution. The agar well diffusion assay exhibited remarkable dose-dependent, wide-spectrum antimicrobial efficacy of the Se NPs against all the tested microorganisms. Moreover, the lowest minimum inhibitory concentration (10 µg/mL) was noted against Salmonella Typhimurium and Fusarium oxysporum. The prepared Se NPs degraded methylene blue dye by about 89% after 6 h of exposure to sunlight. In conclusion, the synthesis of Se NPs using E. indica leaf extract shows promise as a method for producing Se NPs with significant antimicrobial activity and potential for methylene blue photodegradation. These properties make them potentially valuable in various fields, including water treatment and biomedical applications, in the future. Full article
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