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Photonics
Special Issues
Recent Advances in Optics and Photonics for Biosensing and Bioimaging...
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Recent Advances in Optics and Photonics for Biosensing and Bioimaging Applications

A special issue of Photonics (ISSN 2304-6732). This special issue belongs to the section "Biophotonics and Biomedical Optics".

Deadline for manuscript submissions: closed (15 October 2022) | Viewed by 2559

Special Issue Editors

Prof. Dr. Quan Liu

E-Mail Website
Guest Editor
Institute of Electromagnetics and Acoustics, School of Electronic Science and Engineering, Xiamen University, Xiamen 361005, China
Interests: optical spectroscopy; spectral imaging; optical diagnosis; biosensing
Dr. Caigang Zhu

E-Mail Website
Guest Editor
The F. Joseph Halcomb III, M.D. Department of Biomedical Engineering, University of Kentucky, 143 Graham Avenue, Lexington, KY 40506-0108, USA
Interests: optical spectroscopy; optical biosensors; optical microscopy; cancer metabolism
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biosensing and bioimaging techniques based on optics and photonics technology offer the capability of non-destructive detection of biomolecules in a variety of biomedical applications ranging from basic science investigations to clinical diagnosis. The focus of this issue is to provide an interdisciplinary forum for state-of-the-art developments in both fundamental and technological aspects of biosensing and bioimaging fields, including the recent progress and trends in optical sensing, spectroscopy, imaging, and their applications in diagnostics and therapeutics. Those techniques suitable for point-of-care diagnostics in low-resource regions are particularly encouraged. Both original research and review articles are accepted. Topics include but are not limited to:

  • Optical biosensing
  • Optical bioimaging
  • Development of cost-effective devices for optical spectroscopy and imaging
  • Smart phone based optical spectroscopy and imaging
  • Lab-on-chip development for point-of-care optical diagnostics in low-resource regions

Prof. Dr. Quan Liu
Prof. Dr. Caigang Zhu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Photonics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • optical biosensing
  • optical spectroscopy
  • optical imaging
  • point-of-care diagnostics

Published Papers (1 paper)

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Research

7 pages, 1018 KiB  
Communication
Autofluorescence Imaging of Living Yeast Cells with Deep-Ultraviolet Surface Plasmon Resonance
by Che Nur Hamizah Che Lah, Hirofumi Morisawa, Keita Kobayashi, Atsushi Ono, Wataru Inami and Yoshimasa Kawata
Photonics 2022, 9(6), 424; https://doi.org/10.3390/photonics9060424 - 16 Jun 2022
Cited by 2 | Viewed by 1945
Abstract
Autofluorescence in living cells on aluminum thin film was excited with deep-ultraviolet surface plasmon resonance (deep-UV SPR). Deep-UV SPR under aqueous medium was excited with Kretschmann configuration by using a sapphire prism. Deep-UV SPR is one of the promising techniques for high-sensitive autofluorescence [...] Read more.
Autofluorescence in living cells on aluminum thin film was excited with deep-ultraviolet surface plasmon resonance (deep-UV SPR). Deep-UV SPR under aqueous medium was excited with Kretschmann configuration by using a sapphire prism. Deep-UV SPR is one of the promising techniques for high-sensitive autofluorescence imaging of living cells without staining. Label-free observation is significant for the structural analysis of living cells. We demonstrated the high-sensitive autofluorescence imaging of living yeast cells with deep-UV SPR. We applied a high refractive index prism, such as sapphire, which is suitable for the observation of specimens in aqueous medium, to excite deep-UV SPR. Although typical autofluorescence from living cells is buried in background noise, deep-UV SPR enhances the autofluorescence signal. The deep-UV SPR excitation of an aluminum thin film through a sapphire prism was investigated theoretically and experimentally. It showed that the fluorescence intensities are increased 2.8-fold. Deep-UV SPR enhanced the autofluorescence of cell structures, and yeast cells were found to be very sensitive. As a result, for water-immersed specimens, the sapphire-prism-based Kretschmann configuration excited SPR in deep-UV. Findings from this study suggest that deep-UV SPR can be considered an effective technique for attaining high-sensitivity observation of biological samples. Full article
(This article belongs to the Special Issue Recent Advances in Optics and Photonics for Biosensing and Bioimaging Applications)
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