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6.9
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Pharmaceutics
Special Issues
Responsive Nanogels for Drug Delivery
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Responsive Nanogels for Drug Delivery

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 2579

Special Issue Editor

Dr. Manuela Curcio

E-Mail Website
Guest Editor
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy
Interests: design, synthesis and characterization of polymer nanoparticles and hydrogels; synthesis and characterization of stimuli-responsive micro- and nanoparticle systems for controlled drug release
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Stimuli-responsive nanogels are nanoscopic polymeric materials able to modify their physico-chemical properties in response to the application of endogenous or exogenous signals. These kinds of materials—characterized by high stability and loading ability—together with biologic consistencey and high permeation capability, have attracted increasing interest thanks to the subsequent opportunity to obtain delivery systems in which the carrier assumes an active role in the drug delivery process, enabling the optimization of disease therapy. Internal (pH and temperature variations, ROS production, redox potential, enzymes, and glucose) or external (light, electric, or magnetic fields) microenvironmental factors, or a combination of both, can stimulate the response of nanogels, and are useful for the controlled release of bioactive compounds such as drug, genetic materials, or proteins.

This Special Issue is devoted to the most recent developments in the synthesis and characterization of stimuli-responsive nanogels for drug delivery.

Original research papers, communications, or review articles are welcome.

Dr. Manuela Curcio
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanotechnology
  • polymeric nanogels
  • stimuli-responsive delivery
  • targeted delivery

Published Papers (1 paper)

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Review

18 pages, 1543 KiB  
Review
Activity of Povidone in Recent Biomedical Applications with Emphasis on Micro- and Nano Drug Delivery Systems
by Ewelina Waleka, Zbigniew Stojek and Marcin Karbarz
Pharmaceutics 2021, 13(5), 654; https://doi.org/10.3390/pharmaceutics13050654 - 04 May 2021
Cited by 8 | Viewed by 2255
Abstract
Due to the unwanted toxic properties of some drugs, new efficient methods of protection of the organisms against that toxicity are required. New materials are synthesized to effectively disseminate the active substance without affecting the healthy cells. Thus far, a number of polymers [...] Read more.
Due to the unwanted toxic properties of some drugs, new efficient methods of protection of the organisms against that toxicity are required. New materials are synthesized to effectively disseminate the active substance without affecting the healthy cells. Thus far, a number of polymers have been applied to build novel drug delivery systems. One of interesting polymers for this purpose is povidone, pVP. Contrary to other polymeric materials, the synthesis of povidone nanoparticles can take place under various condition, due to good solubility of this polymer in several organic and inorganic solvents. Moreover, povidone is known as nontoxic, non-carcinogenic, and temperature-insensitive substance. Its flexible design and the presence of various functional groups allow connection with the hydrophobic and hydrophilic drugs. It is worth noting, that pVP is regarded as an ecofriendly substance. Despite wide application of pVP in medicine, it was not often selected for the production of drug carriers. This review article is focused on recent reports on the role povidone can play in micro- and nano drug delivery systems. Advantages and possible threats resulting from the use of povidone are indicated. Moreover, popular biomedical aspects are discussed. Full article
(This article belongs to the Special Issue Responsive Nanogels for Drug Delivery)
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