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Special Issue "Biodegradable Formulations for Ocular Drug Delivery"
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 30 June 2023 | Viewed by 3834
Special Issue Editors
Interests: drug delivery systems; eye diseases; pharmaceutical development; biopharmacy
2. Miguel Servet Ophthalmology Research Group (GIMSO), Aragon Health Research Institute (IIS Aragon), University of Zaragoza, 50009 Zaragoza, Spain
Interests: optic neuropathy; glaucoma; neuro-ophthalmology; ocular drug delivery; optic coherence tomography
Special Issue Information
The treatment of ocular pathology is challenging. It is necessary to reach the target cell and maintain effective concentrations at the site of action. Drug penetration, drug metabolism, and cell–drug interactions are influenced by the surrounding cellular microenvironment and the pathological stage. There is currently a demand to develop ophthalmic formulations based on personalized medicine and focused on the individual needs of each patient. In addition, there is a search for new formulations that minimize iatrogenesis, patient discomfort, and costs. In recent decades, several technological approaches based on nano- and microtechnology, in situ hydrogel systems, implants, or inserts have proven to be powerful tools for more efficient delivery of active substances to both the anterior and posterior segments of the eye. The biomaterials used to prepare these systems must be highly biocompatible with the delicate ocular structures. In this sense, biodegradable drug delivery systems are generally preferred as they disappear from the administration site once they have released their content. In addition, from a technological point of view, there are still important issues to address and resolve, such as sterilization of these systems or their long-term stability and storage. This Special Issue is open to original research articles, review articles, or mini-reviews in this field covering technological, methodological, pharmacological (in vitro, ex vivo and in vivo), or biochemical approaches to biodegradable ophthalmic formulations for the treatment of ocular pathology, but also for a potential application for early diagnosis.
Dr. Irene Bravo-Osuna
Dr. María Jesús Rodrigo Sanjuán
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- intraocular drug delivery system
- optic neuropathy
- retinal disease
- ocular surface disease
- nanosystems for ocular drug delivery
- personalized medicine
- microsystems for ocular drug delivery
- early diagnosis
- ocular implants and inserts
- hydrogels for ocular drug delivery