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Special Issue "Solid Dispersions for Bioavailability Enhancement"
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 31 August 2023 | Viewed by 579
Special Issue Editor
Interests: amorphous solid dispersions; bioavailability enhancement; enabling formulations; biorelevant in vitro models; in vitro–in vivo correlation; PK prediction
Special Issue Information
I am pleased to invite you to contribute to this Special Issue intended to highlight new advances in solid dispersions for bioavailability enhancement. Solid dispersions (SDs) have gained considerable attention in recent years as one of the most promising approaches to enhance the bioavailability of poorly soluble drugs. SDs can be prepared using various techniques, such as spray-drying and hot melt extrusion, by dispersing a poorly soluble drug in a polymeric matrix, which prevents drug crystallization and enhances both the solubility and the dissolution rate.
This Special Issue aims to provide a comprehensive overview of the recent advances in the field of SDs for bioavailability enhancement covering the development, characterization, and evaluation of SDs, as well as their applications in drug delivery. The collection of articles will hopefully contribute to advancements in the field, and ultimately, the development of more effective and safe medicines for patients.
The Special Issue serves as a platform for researchers to present their latest findings and insights in this rapidly growing field and welcomes original research articles and reviews that cover various aspects of SDs for bioavailability enhancement including (but not limited to) the following:
- Development and optimization of SDs using various techniques;
- Physical and chemical characterization of SDs;
- Evaluation of the in vitro and in vivo performance of SDs;
- Mechanistic understanding of the behavior of SDs;
- Regulatory considerations and challenges in the development of SDs.
I look forward to receiving your contributions.
Dr. Matthias Manne Knopp
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- solid dispersions
- bioavailability enhancement
- solubility enhancement
- drug–polymer interactions
- physical stability
- in vivo pharmacokinetics