Special Issue "Feature Reviews in Medicinal Chemistry"
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 22614
Interests: anticancer drug design; breast cancer; novel antioestrogens; tubulin targeting agents; azetidinones; antioestrogen–drug conjugates; oestrogen receptor; Burkitt's lymphoma; chronic lymphocytic leukaemia
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The Medicinal Chemistry section of Pharmaceuticals invites high-quality reviews contributing towards our understanding of the relationship between the molecular structure and biological activity of drug molecules. The relevant topics in this Special Issue include the discovery, design and synthesis of biologically active compounds, together with the interpretation of their structure–activity relationships and mechanism of action at the molecular level. Our aim is to include outstanding reviews covering all aspects of small molecules as clinical drug candidates, e.g., drug discovery and design, combinatorial chemistry, molecular modelling and bioinformatics. Suitable topics also include novel synthetic routes for drug candidates, leading discovery and optimization methods, structure-based drug design, crystal structure analysis and drug metabolism. In addition, the identification and validation of novel drug targets, high-throughput screening methodologies, virtual screening techniques, database mining and machine learning in drug discovery are included in the scope of topics for these reviews. Chemical biology and structural studies which investigate chemical probes and the molecular recognition processes identified in the action of biologically active molecules are particularly welcome. Reviews which describe novel strategies and methodologies with relevant applications in chemical biology and medicinal chemistry are also welcome.
Submissions to the Special Issue must include a cover letter indicating the novelty of the review article in relation to reviews published in the literature. A 20% discount will be applied to the Article Processing Charges (APCs).
Prof. Dr. Mary J. Meegan
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- drug discovery, design and synthesis
- structure–activity relationships
- molecular modelling
- novel drug targets
- high-throughput screening
- drug metabolism
- drug analytical methods