Immunology and Virology of Epstein–Barr Virus Infection
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".
Deadline for manuscript submissions: 30 April 2024 | Viewed by 268
Special Issue Editors
Interests: viral hepatitis; hepatitis C; HIV; virology; immunology
Special Issues, Collections and Topics in MDPI journals
Interests: tumor biology; molecular pathology; medical genetics; cell biology; genomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Epstein–Barr virus (EBV) is a member of the Herpesviridae family and is considered to be a prototypic oncogenic virus that enables transformation of B-cells into B-lymphoblastoid cell lines in vitro by using complex molecular mechanisms. Molecular diversity of EBV is exceptionally complex and includes classification into genotypes, genetic variants (based on gene diversity) and phylogroups. Molecular mechanisms of complex interactions between the immune and specific host immunity and EBV during both latent and lytic stages of the replication cycle are a particular focus of interest in recent years. EBV infection is associated with significant morbidity and mortality associated with malignant and non-malignant diseases. Recent data on the association between EBV infection and the risk of developing multiple sclerosis renewed the interest of the scientific community in the development of prophylactic vaccines. This Special Issue will focus on the most recent developments in the elucidation of complex molecular networks in innate and specific immune responses to EBV in vitro and in vivo and an association between particular features of the immune response with molecular diversity of the virus. Scientific advances in EBV immunology and virology will also be considered within the context of other herpesviruses with distinct biological features of their own. In addition, the issue will especially welcome an update on recent developments in prophylactic and therapeutic candidate EBV vaccine evaluations.
Dr. S. Zidovec Lepej
Dr. Petra Korać
Guest Editors
Manuscript Submission Information
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Keywords
- Epstein–Barr virus
- herpesviruses
- immunity
- genotyping
- immune evasion
- oncology
