Advances in the Diagnosis, Detection, Epidemiology, and Control of Toxoplasma gondii
Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 25770
Interests: epidemiology; biology; transmission; humans; livestock animals; wild animals; coccidia; protozoan parasites; zoonotic parasites; Toxoplasma gondii; Neospora spp.; Besnoitia spp.; Hammondia spp.; Cryptosporidium spp.; Sarcocystis spp.; phylogenetics; genotyping diagnosis and epidemiology of Toxoplasma gondii
Interests: parasitology; Giardia; protein-protein interaction; cell biology; genotyping; Toxoplasma; Molecular Diagnostic
Toxoplasma gondii is one of the most important zoonotic parasites in the world. Several routes of infection are possible in animals and humans and three different parasitic stages (oocysts, tissue cysts, and tachyzoites) are involved. In addition, a genetically diverse population, consisting of an increasing number of diverse haplogroups with different virulence characteristics for individual infected host species, further complicates our understanding of this parasite’s epidemiology. Moreover, T. gondii has an extremely broad host spectrum and parasitic stages, such as infectious tissue cysts, contaminate edible tissues of meat-producing animals and represent the most important source of human infection. Other sources of infection include viable oocysts, which may contaminate drinking water, fruits and vegetables, and even seafood. Different hosts, host tissues, and host materials, and the large variety of contaminated matrices, including water and vegetables, often make diagnosis and detection a difficult endeavor. Despite continuing efforts, drug options for toxoplasmosis are scarce, often require combinational therapy, result in poor compliance with a spectrum of adverse events, and are unable to eliminate T. gondii cysts from the infected host. Vaccination approaches would be ideal considering the zoonotic nature of toxoplasmosis.
This Special Issue aims to present a collection of articles on novel diagnostic and detection techniques, their improvement, standardization, and harmonization, and their application in studies to elucidate the epidemiology and transmission of T. gondii as well its genetic composition. Studies exploring new promising drug treatment and vaccination approaches, especially in animals, are also welcome.
Dr. Gereon R. M. Schares
Dr. Marco Lalle
Prof. Dr. Olgica Durkovic-Dakovic
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Toxoplasma gondii
- molecular diagnosis
- wild animals
- fresh produce
- drinking water