Advances in African Swine Fever Virus
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 954
Special Issue Editors
Interests: virus; pathogenicity; innate immune; signaling pathway; host–virus interaction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
African swine fever (ASF) is a highly contagious infectious disease caused by African swine fever virus (ASFV). ASFV-infected domestic pigs and wild boars have a mortality rate as high as 100%. Since there is no commercial vaccine available to prevent ASF, it has spread rapidly and caused a great challenge for the swine industry worldwide. ASFV encodes more than 167 proteins that not only execute their functions in virus replication, but also regulate host antiviral immune responses. The ASFV proteins E248R and E199L are involved in membrane fusion, and DP71L, A224L and EP424R regulate viral translation. Some ASFV proteins, such as MGF_505-7R, E120R, DP96R, A137R, I215L and MGF_360-12L, inhibit the innate immune response via different mechanisms. However, the pathogenesis, immune evasion and immune protection mechanism of ASFV are still not fully understood, limiting the development of safe and effective ASF vaccines. Therefore, it is urgent to study the molecular and cellular mechanisms of ASFV escaping innate and adaptive immune responses in the host.
This Special Issue aims to explore the pathogenesis, immune evasion and immune protective mechanism of ASFV and provide theoretical support for the design and development of novel effective ASFV vaccines.
Dr. Li Huang
Dr. Dan Li
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
