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Metals
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Advanced Biomedical Materials (Volume 2)
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Advanced Biomedical Materials (Volume 2)

A special issue of Metals (ISSN 2075-4701). This special issue belongs to the section "Biobased and Biodegradable Metals".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 1717

Special Issue Editors

Dr. Lin Mao

E-Mail Website
Guest Editor
Associate Professor, School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Interests: biomaterials; material synthesis; biodegradable Mg alloy; biocompatibility; surface treatment; structural characterization; mechanical property
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Xiaobo Zhang

E-Mail Website
Guest Editor
School of Materials Science and Engineering, Nanjing Institute of Technology, Nanjing 211167, China
Interests: biomaterials; material synthesis; material processing, biodegradable Mg alloy; biocompatibility; material characterization; mechanical property
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biomedical materials are defined as substances that have been engineered, manufactured, or processed to be suitable for use as medical devices (or components thereof) and that are usually intended to be used as artificial materials in the human body for the purposes of aiding healing, correcting deformities, and restoring lost function. Biomedical materials have undergone three of stages development. First-generation biomedical materials are usually those materials which are biocompatible and bioinert in the human body. Second-generation biomedical materials are designed to meet more application requirements with either resorbable or bioactive properties. Third-generation biomedical materials combine these two properties and are designed to serve as an extracellular matrix for activating genes and eliciting specific interactions with cell and, thereby, to direct cell proliferation, differentiation, organization, and ultimately repair or regenerate living tissues and organs. The field of biomedical materials continues to be one of the most rapidly growing areas of research today, and this burgeoning field has become strongly interdisciplinary, encompassing new materials and their interactions with components of living systems and emphasizing the fundamental materials science, structure–property relationships, and biological responses as a foundation for a wide array of biomedical materials applications.

The Special Issue coverage spans a wide range of topics from basic science to clinical applications, around the theme of preparation, performance, and evaluation of advanced biomedical materials; the chemical, physical, toxicological, and mechanical behavior of materials in physiological environments; and the response of blood and tissues to biomedical materials. The scope of the Special Issue also covers studies in interdisciplinary areas such as tissue engineering and medical devices, where biomedical materials play a significant role in the therapeutic or diagnostic procedure.

Dr. Lin Mao
Prof. Dr. Xiaobo Zhang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomedical materials
  • material synthesis
  • structural characterization
  • mechanical property
  • medical device
  • structural design
  • finite element analysis
  • biocompatibility

Published Papers (2 papers)

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12 pages, 3488 KiB  
Article
Mechanical Properties and In Vitro Corrosion Behaviors of Biodegradable Magnesium Alloy Suture Anchors
by Lin Mao, Zhiwei Dai, Xue Cai, Zhongxin Hu, Jian Zhang and Chengli Song
Metals 2024, 14(3), 288; https://doi.org/10.3390/met14030288 - 29 Feb 2024
Viewed by 730
Abstract
Biodegradable suture anchors based on Mg-Nd-Zn-Zr alloy were developed for ligament-to-bone fixation in rotator cuff surgeries. The Mg alloy anchors were designed with structural features of narrow tooth and wide tooth, and simulated through finite element analysis (FEA). Meanwhile, the corrosion behaviors of [...] Read more.
Biodegradable suture anchors based on Mg-Nd-Zn-Zr alloy were developed for ligament-to-bone fixation in rotator cuff surgeries. The Mg alloy anchors were designed with structural features of narrow tooth and wide tooth, and simulated through finite element analysis (FEA). Meanwhile, the corrosion behaviors of the Mg alloy anchors were studied by immersion test and the mechanical properties were investigated by measuring the maximum torque and pull-out force. The simulation result showed that the wide-tooth anchor exhibited more a uniform stress distribution and lower shear stress in the torsion process, suggesting a satisfactory torsional resistance of this structure. Meanwhile, the wide-tooth anchor exhibited a lower Von-Mises stress after applying the same pull-out force in the simulation, indicating a higher resistance to pull-out failure of the anchor. The result of the immersion test indicated that the wide-tooth anchor exhibited a slightly slower corrosion rate in Hank’s solution after 14-day immersion, which was beneficial to enhance the structural and mechanical stability of the biodegradable suture anchor. Furthermore, the results of the mechanical properties test demonstrated that the wide-tooth anchor showed superior performance with higher maximum torques and axial pull-out forces before and after corrosion. More importantly, the axial pull-out force and maximum torque for the wide-tooth anchor decreased by 5.86% and 8.64% after corrosion, which were significantly less than those for the narrow-tooth anchor. Therefore, the wide-tooth suture anchor with lower corrosion rate, higher mechanical properties and structural stability is a promising candidate for ligament-bone fixation in the repair of rotator cuff injuries. Full article
(This article belongs to the Special Issue Advanced Biomedical Materials (Volume 2))
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16 pages, 6890 KiB  
Article
Crystallization of Zr-Based Amorphous Alloys in Laser Welding
by Shiju Yan, Chengli Song, Lingling Huang, Liang Han and Chengyong Wang
Metals 2023, 13(7), 1283; https://doi.org/10.3390/met13071283 - 17 Jul 2023
Viewed by 706
Abstract
Crystallization often occurs in the laser welding of amorphous alloys, reducing the properties of amorphous alloys. Therefore, the research in this thesis focuses on the experimental selection of suitable welding parameters to prevent crystallization of Zr-based amorphous alloys during the laser welding process. [...] Read more.
Crystallization often occurs in the laser welding of amorphous alloys, reducing the properties of amorphous alloys. Therefore, the research in this thesis focuses on the experimental selection of suitable welding parameters to prevent crystallization of Zr-based amorphous alloys during the laser welding process. As such, it is necessary to simulate the temperature field curve of the welding area by computer and then determine the power and laser moving speed of laser welding. In this paper, the temperature field curve of the Zr41.2Ti13.8Cu12.5Ni10Be22.5 (Vit1) amorphous alloy in laser welding is obtained by finite element analysis. The continuous heating curve (CHT) of Vit1 is fitted by the Vogel–Fulcher–Tammann (VFT) equation and the Kissinger equation. If the temperature field curve intersects with the CHT curve, crystallization occurs. The experiment results show that the VFT equation can be used to predict the crystallization of Vit1 better in laser welding. The temperature and welding time are increased by using a low welding speed. Therefore, the temperature of the weld zone cannot fall in time, resulting in the intersection of the temperature field curve and the CHT curve. Thus, crystallization can be avoided if the welding speed is controlled within a reasonable range, and the highest temperature is kept under the CHT curve. The combination of the CHT curve and the temperature field curve shows that the samples at 300 W-3 mm/s and 300 W-6 mm/s welding parameters all undergo crystallization, while the samples at 300 W-9 mm/s and 300 W-12 mm/s welding parameters do not undergo crystallization. Through the flexural test, it is found that the flexural strength of the welded interface is at its the maximum under 300 W-9 mm/s. Full article
(This article belongs to the Special Issue Advanced Biomedical Materials (Volume 2))
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