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Biocompatible Nanostructures: Research, Development, and Applications

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Advanced Nanomaterials and Nanotechnology".

Deadline for manuscript submissions: closed (20 July 2023) | Viewed by 2502

Special Issue Editors


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Guest Editor
Physics Department, Center for Research and Advanced Studies of the National Polytechnic Institute, CINVESTAV-IPN, Ciudad de México 07360, Mexico
Interests: solid state physics; synthesis of nanoparticles; theranostics; electron microscopy; scanning probe microscopy
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Interdisciplinary Research Laboratory (LII), Nanostructures and Biomaterials Area, Escuela Nacional de Estudios Superiores Unidad León, Universidad Nacional Autónoma de México, Predio el Saucillo y el Potrero, Comunidad de los Tepetates, León 37684, Mexico
Interests: nanostructures; biomedical applications; cancer theranostics; antimicrobial applications; 3D cell models; biomaterials; 2D structures

Special Issue Information

Dear Colleagues,

Nanomedicine—the booming applications of various nanostructures concerning biomedical applications—has become a promising alternative with significant challenges. Nonetheless, it depends on multiple factors to reach the clinical trial. One such aspect is biocompatibility, which is investigated quite often by functionalizing with versatile compounds to perform its function by majorly minimizing the toxic effect and without eliciting any undesirable effects in specific applications. More than developing and designing a novel nanostructure, the main concern among investigators leads to testing and evaluating biocompatibility and biodegradability. These factors are also considered to be essential criteria which need to be addressed, and it is urgent to define the specific administration behavior for nanotherapies and diagnosis.

This Special Issue on “Biocompatible nanostructures: Research, Development and Applications” aims to discuss state-of-the-art research on biocompatible nanostructures and biomedicine as well as developments in synthesis, biofunctionalization, properties, and biomedical applications. This extends to recent highlights in our comprehension of biocompatible nanostructures and their suitability for therapeutics, diagnoses, sensing, and implant applications, including nanobioanalysis in vitro and nanotoxicity.

Contributions such as full papers, communications, and reviews are welcome, focusing on new advances and strategies with unlimited configurations of biocompatible nanostructures.

Prof. Dr. Jaime Santoyo-Salazar
Dr. Ravichandran Manisekaran
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

23 pages, 4522 KiB  
Article
Processing and Physicochemical Properties of Magnetite Nanoparticles Coated with Curcuma longa L. Extract
by Margarita L. Alvarado-Noguez, Ana E. Matías-Reyes, Mario Pérez-González, Sergio A. Tomás, Claudia Hernández-Aguilar, Flavio A. Domínguez-Pacheco, Jesús A. Arenas-Alatorre, Alfredo Cruz-Orea, Mauricio D. Carbajal-Tinoco, Jairo Galot-Linaldi, Elizabet Estrada-Muñiz, Libia Vega-Loyo and Jaime Santoyo-Salazar
Materials 2023, 16(8), 3020; https://doi.org/10.3390/ma16083020 - 11 Apr 2023
Cited by 3 | Viewed by 2051
Abstract
In this work, Curcuma longa L. extract has been used in the synthesis and direct coating of magnetite (Fe3O4) nanoparticles ~12 nm, providing a surface layer of polyphenol groups (–OH and –COOH). This contributes to the development of nanocarriers [...] Read more.
In this work, Curcuma longa L. extract has been used in the synthesis and direct coating of magnetite (Fe3O4) nanoparticles ~12 nm, providing a surface layer of polyphenol groups (–OH and –COOH). This contributes to the development of nanocarriers and triggers different bio-applications. Curcuma longa L. is part of the ginger family (Zingiberaceae); the extracts of this plant contain a polyphenol structure compound, and it has an affinity to be linked to Fe ions. The nanoparticles’ magnetization obtained corresponded to close hysteresis loop Ms = 8.81 emu/g, coercive field Hc = 26.67 Oe, and low remanence energy as iron oxide superparamagnetic nanoparticles (SPIONs). Furthermore, the synthesized nanoparticles (G-M@T) showed tunable single magnetic domain interactions with uniaxial anisotropy as addressable cores at 90–180°. Surface analysis revealed characteristic peaks of Fe 2p, O 1s, and C 1s. From the last one, it was possible to obtain the C–O, C=O, –OH bonds, achieving an acceptable connection with the HepG2 cell line. The G-M@T nanoparticles do not induce cell toxicity in human peripheral blood mononuclear cells or HepG2 cells in vitro, but they can increase the mitochondrial and lysosomal activity in HepG2 cells, probably related to an apoptotic cell death induction or to a stress response due to the high concentration of iron within the cell. Full article
(This article belongs to the Special Issue Biocompatible Nanostructures: Research, Development, and Applications)
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