Marine Biotoxins 3.0
A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Toxins".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 2046
Special Issue Editor
Interests: natural toxins from marine and terrestrial organisms; voltage-gated ion channels; ligand gated channels; nicotinic acetylcholine receptors; cholinesterases; IP3 receptors; cell signaling; synaptic transmission; neuromuscular transmission; transmitter release
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In this new Special Issue of “Marine Biotoxins 3.0”, we welcome manuscripts dealing with microorganisms involved in the production of marine biotoxins (bacteria, cyanobacteria, dinoflagellates, diatoms, and fungi), the environmental factors favoring their proliferation, and their vectorial transfer through the marine food web. The transfer of marine biotoxins to invertebrates, fish, birds, and marine mammals constitutes a menace for wildlife. Some marine biotoxins definitely constitute a threat for human consumers of contaminated shellfish and fish, and regulatory limits need to be evaluated and discussed in order to set risk factors. Most marine biotoxins belong to different families of organic molecules, with diverse and rich chemical structures, and new biotoxins are described every year. The cellular targets on which marine biotoxins may act are numerous and include (i) ion channels (voltage-gated Na+, K+, or Ca2+ channels); (ii) ionotropic receptors or ligand-gated channels—such as glutamate receptors (AMPA, Kainate, and NMDA receptors), nicotinic acetylcholine receptors, serotonin 3 (5HT3) receptors, and γ-aminobutyric acid (GABAA receptors); (iii) metabotropic receptors, including G-protein coupled receptors, coupled to adenylate cyclase (GS, Gi/o), or to phospholipase C-β; (iv) other targets of marine biotoxins include intracellular cytosolic and nuclear receptors that may affect mRNA and protein transcription; and (v) the role of second messengers such as calcium, inositol trisphosphate (IP3), and diacylglycerol, which is also another important aspect of the mode of action of marine toxins that needs to be better known. Therefore, the better we know the cellular and molecular target(s), signaling pathways and mechanism(s) used by marine biotoxins to exert their toxic activities, the more possibilities we will have to find putative antagonists or effective countermeasures.
Prof. Dr. Jordi Molgó
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- marine biotoxins
- mechanism of action
- pharmacology
- cellular and molecular targets
- signaling pathways
- metabolism
- toxicity
- risk factors
- molecular interactions
- therapeutic potential
