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Life
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Current Research on Optic Nerve Ultrasound Evaluation
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Current Research on Optic Nerve Ultrasound Evaluation

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Radiobiology and Nuclear Medicine".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 7708

Special Issue Editor

Dr. Livio Vitiello

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Guest Editor
Eye Unit "Luigi Curto" Hospital, Azienda Sanitaria Locale Salerno, 84035 Polla, Salerno, Italy
Interests: ophthalmology; medical retina; ocular ultrasound; optical coherence tomography; OCT; optic nerve diseases; glaucoma
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Despite recent advances in ophthalmic technology, the presence of papilledema, a sign of possible intracranial hypertension or optic nerve disease, can often be really challenging. Finding a way to make such a differential diagnosis and to follow up these patients with a noninvasive and easily achievable technique could provide a correct management approach and improve patient recovery.

Ocular ultrasonography is well known to be a repeatable, non-invasive, and trustworthy technique for studying several eye and orbital diseases. Among these, optic nerve studies have been carried out, aiming to prove the usefulness and accuracy of this diagnostic tool in the differential diagnosis of these diseases, with conflicting results.

The aim of this Special Issue will be to promote research on the role of ultrasound in the differential diagnosis of optic nerve diseases and in the evaluation of optic nerve changes in different clinical and surgical settings.

Dr. Livio Vitiello
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ocular ultrasonography
  • optic nerve
  • optic nerve sheath diameter
  • ONSD
  • ultrasound

Published Papers (3 papers)

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Research

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10 pages, 962 KiB  
Article
Optic Nerve Sheath Diameter: A Cross-Sectional Study of Ultrasonographic Measurement in Healthy Black South African Adults
by Lindy Trollip, Kerry Alberto and Aubrey Makgotloe
Life 2023, 13(10), 1979; https://doi.org/10.3390/life13101979 - 28 Sep 2023
Viewed by 1016
Abstract
Ultrasonographic optic nerve sheath diameter (ONSD) measurement is an accurate, portable, and non-invasive method of detecting raised intracranial pressure that can also reflect dynamic, real-time changes in intracranial pressure fluctuations. Various studies have shown the mean range of ONSD to vary greatly across [...] Read more.
Ultrasonographic optic nerve sheath diameter (ONSD) measurement is an accurate, portable, and non-invasive method of detecting raised intracranial pressure that can also reflect dynamic, real-time changes in intracranial pressure fluctuations. Various studies have shown the mean range of ONSD to vary greatly across different population groups. This study aimed to determine the mean ONSD in healthy Black South African adults. In this cross-sectional study, healthy black South African adult participants underwent optic nerve sheath ultrasound of the right eye, with the diameter being measured at 3 mm behind the retina in two different planes. The average of the two measurements was used to find the mean optic nerve sheath diameter. This measurement was compared to that found in a Canadian adult population, and the effect of age, gender, and co-morbidities on ONSD was assessed. A total of 99 participants were included in this study, of which 39 were male and 60 were female. The mean ONSD was found to be 5.1 mm (SD ± 0.33). This value was significantly higher than the mean ONSD observed in the Canadian population (p < 0.001). There was no significant difference found between the mean ONSD in males and females (p = 0.652), and both age and presence of co-morbidities were not found to significantly correlate with ONSD. (p = 0.693 and p = 0.974, respectively). Full article
(This article belongs to the Special Issue Current Research on Optic Nerve Ultrasound Evaluation)
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10 pages, 1403 KiB  
Communication
OCTA and Doppler Ultrasound in Primary Open-Angle Glaucoma and Normal-Tension Glaucoma
by Jan Lestak, Martin Fus, Marain Rybář and Antonin Benda
Life 2023, 13(3), 610; https://doi.org/10.3390/life13030610 - 22 Feb 2023
Cited by 2 | Viewed by 1443
Abstract
The aim of this study was to determine whether the values of vessel density (VD) and perfusion parameters in the ophthalmic artery (OA) and central retinal artery (CRA) of the same eye differ in patients with hypertensive glaucoma (HTG) from patients with normotensive [...] Read more.
The aim of this study was to determine whether the values of vessel density (VD) and perfusion parameters in the ophthalmic artery (OA) and central retinal artery (CRA) of the same eye differ in patients with hypertensive glaucoma (HTG) from patients with normotensive glaucoma (NTG). The first group consisted of 20 HTG patients (40 eyes). Patients with HTG were verified to have primary open-angle glaucoma (POAG). The second group consisted of 20 HTG patients (40 eyes). VD was used to determine the Avanti RTVue XR from Optovue (USA). Peak systolic velocity (PSV), end-diastolic velocity (EDV) and resistance index (RI) were measured in both the central retinal artery (CRA) and ophthalmic artery (OA) using Doppler sonography on the Affinity 70G from Philips (USA). The visual field (VF) was examined by a fast threshold glaucoma program using a Medmont M700 (Australia). We showed no differences in VF, VD, PSV-OA and EDV-CRA between the two groups. Statistically significant differences between the two groups were observed in PSV in CRA (p = 0.04), EDV in OA (p = 0.009) and in RI in both CRA and OA. Other values were without significant differences in both groups. In both HTG and NTG, we observed in PSV-CRA, EDV-OA, RI-CRA and RI-OA. Full article
(This article belongs to the Special Issue Current Research on Optic Nerve Ultrasound Evaluation)
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Review

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21 pages, 1737 KiB  
Review
A Narrative Review of Point of Care Ultrasound Assessment of the Optic Nerve in Emergency Medicine
by Torey Lau, Justin S. Ahn, Rahim Manji and Daniel J. Kim
Life 2023, 13(2), 531; https://doi.org/10.3390/life13020531 - 15 Feb 2023
Cited by 4 | Viewed by 4732
Abstract
Point of care ultrasound (POCUS) of the optic nerve is easy to learn and has great diagnostic potential. Within emergency medicine, research has primarily focused on its use for the assessment of increased intracranial pressure, but many other applications exist, though the literature [...] Read more.
Point of care ultrasound (POCUS) of the optic nerve is easy to learn and has great diagnostic potential. Within emergency medicine, research has primarily focused on its use for the assessment of increased intracranial pressure, but many other applications exist, though the literature is heterogeneous and largely observational. This narrative review describes the principles of POCUS of the optic nerve including anatomy and scanning technique, as well as a summary of its best studied clinical applications of relevance in emergency medicine: increased intracranial pressure, idiopathic intracranial hypertension, optic neuritis, acute mountain sickness, and pediatric intracranial pressure assessment. In many of these applications, sonographic optic nerve sheath diameter (ONSD) has moderately high sensitivity and specificity, but the supporting studies are heterogeneous. Further studies should focus on standardization of the measurement of ONSD, establishment of consistent diagnostic thresholds for elevated intracranial pressure, and automation of ONSD measurement. Full article
(This article belongs to the Special Issue Current Research on Optic Nerve Ultrasound Evaluation)
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