New Insights into the Treatment of Valvular Heart Disease

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 1019

Special Issue Editors


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Guest Editor
Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy Iasi, 16 University Street, 700115 Iasi, Romania
Interests: cardiology; internal medicine; heart failure; atherosclerosis; arterial hypertension
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Guest Editor
Faculty of Medicine, “George Emil Palade” University o Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 54042 Targu Mures, Romania
Interests: vulnerable plaques; atherosclerosis; heart failure; acute coronary syndromes; interventional cardiology
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Guest Editor
Faculty of Medicine, “Victor Babes” University of Medicine and Pharmacy Timisoara, Square Eftimie Murgu No. 2, 30041 Timisoara, Romania
Interests: cardiology; internal medicine; heart failure; atherosclerosis; arterial hypertension
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cardiovascular diseases represent the main cause of mortality worldwide, and valvular heart diseases (VHD) are among the most frequent. In recent years, the interventional treatment of VHD, mainly via transcatheter aortic valve replacement (TAVI), has begun to replace traditional open heart surgery for aortic valve corrections in many health centers, and has rapidly become the first-option therapy for several clinical conditions; meanwhile, interventional mitral valve correction using MitraClip devices has demonstrated good results in patients with heart failure and mitral insufficiency. The immediate and long-term results of an interventional procedure depend largely on the complexity and the accuracy of the image-based pre-operative assessment of the lesions. As a result of the impressive technological progress made in recent years, many new cardiac imaging methods have been developed that aim to better characterize heart diseases and provide the necessary information required for complex cardiac interventions. These include new applications of advanced 3D echocardiography and multislice cardiac computed tomography with computerized and complex 3D-based reconstructions of cardiac structures.

This Special Issue will highlight the most recent advances in the diagnostics and treatment of VHD, focusing on multimodal imaging for diagnosing VHD, modern technologies for pre-intervention assessment, and novel therapeutic techniques for the correction of diseased valves.   

Prof. Dr. Ciprian Rezus
Dr. Theodora Benedek
Prof. Dr. Daniel Florin Lighezan
Guest Editors

Manuscript Submission Information

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Keywords

  • valvular heart diseases
  • imaging
  • TAVI

Published Papers (1 paper)

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Review

20 pages, 305 KiB  
Review
Modern Treatment of Valvulopathies in Patients with Congenital Hemophilia
by Minerva Codruta Badescu, Oana Viola Badulescu, Liliana Gheorghe, Lăcrămioara Ionela Butnariu, Anca Ouatu, Diana Popescu, Oana Nicoleta Buliga-Finiș, Eusebiu Vlad Gorduza, Manuela Ciocoiu and Ciprian Rezus
Life 2024, 14(3), 354; https://doi.org/10.3390/life14030354 - 7 Mar 2024
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Abstract
Hemophiliacs can develop cardiovascular diseases, including valvulopathies of various etiologies and severities. Some require surgical treatment. Performing cardiac surgery in hemophiliacs is a challenge because they maintain an increased risk of bleeding throughout their lives. Our review shows that with a multidisciplinary team [...] Read more.
Hemophiliacs can develop cardiovascular diseases, including valvulopathies of various etiologies and severities. Some require surgical treatment. Performing cardiac surgery in hemophiliacs is a challenge because they maintain an increased risk of bleeding throughout their lives. Our review shows that with a multidisciplinary team and careful planning, cardiac surgery can be safely performed in these patients. Valve repair and bioprosthetic valves should be preferred over mechanical valves to avoid life-long anticoagulation. In patients who cannot receive a bioprosthetic valve, the use of the On-X mechanical valve might be considered because it requires less intensive anticoagulation after 3 months of treatment. Antithrombotic treatment is feasible in hemophiliacs only if the coagulation factor level is kept constantly above a specific trough limit. Our review is valuable because, for the first time, the available data on the modern surgical treatment of valvular disease in hemophiliacs have been synthesized and systematized. Full article
(This article belongs to the Special Issue New Insights into the Treatment of Valvular Heart Disease)
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