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Life
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Recent Advances in Modern Thoracic Surgery
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Recent Advances in Modern Thoracic Surgery

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 14 June 2024 | Viewed by 2037

Special Issue Editor

Dr. Alessandro Gonfiotti

E-Mail Website
Guest Editor
Department of Clinical and Experimental Medicine, University of Florence, 3-50134 Firenze, Italy
Interests: cardiothoracic surgery; radio-guided thoracic surgery; mediastinal tumors surgery; tracheal surgery; minimally invasive thoracic surgery; surgery of mesothelioma; lung cancer staging and treatment; video-assisted sympathectomy for essential hyperhidrosis; surgery of bullous emphysema; lung volume reduction surgery; video-assisted thoracic surgery

Special Issue Information

Dear Colleagues,

Thoracic surgery has evolved extensively in recent decades. Although thoracic surgeons still mainly deal with neoplastic lesions in the lungs, mediastinum, and pleura, they now treat their patients using mainly minimally invasive and lung-sparing techniques. Minimally invasive thoracic procedures include robot-assisted thoracic surgery and uniportal video-assisted thoracic surgery. Novel techniques for sublobar resection, including virtual pre-operative three-dimensional (3D) lung mapping, image-guided video-assisted thoracic surgery, and segmentectomy using indocyanine green, are increasingly used in daily practice.

Severe donor shortage remains the biggest limit for lung transplantation; however, new options of marginal donors, including donation after circulatory death and ex vivo lung perfusion, are attempting to overcome this limit. Herein, we provide the most recent and important current issues a general thoracic surgeon encounters during routine clinical practice.

Dr. Alessandro Gonfiotti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • video-assisted thoracic surgery
  • robotic surgery
  • three-dimensional computed tomography
  • uniportal surgery
  • lung transplantation

Published Papers (2 papers)

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Research

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10 pages, 507 KiB  
Article
The Feasibility of Less-Invasive Bentall Surgery: A Real-World Analysis
by Antonia van Kampen, Christian D. Etz, Josephina Haunschild, Martin Misfeld, Piroze Davierwala, Sergey Leontyev and Michael A. Borger
Life 2023, 13(11), 2204; https://doi.org/10.3390/life13112204 - 13 Nov 2023
Viewed by 745
Abstract
Objective: Minimally invasive approaches are being used increasingly in cardiac surgery and applied in a wider range of operations, including complex aortic procedures. The aim of this study was to examine the safety and feasibility of a partial upper sternotomy approach for isolated [...] Read more.
Objective: Minimally invasive approaches are being used increasingly in cardiac surgery and applied in a wider range of operations, including complex aortic procedures. The aim of this study was to examine the safety and feasibility of a partial upper sternotomy approach for isolated elective aortic root replacement (a modified Bentall procedure). Methods: We performed a retrospective analysis of 768 consecutive patients who had undergone isolated Bentall surgery between January 2000 and January 2021 at our institution, with the exclusion of re-operations, endocarditis, acute aortic dissections, and root replacement with major concomitant procedures such as multi-valve or coronary bypass surgery. A total of 98 patients were operated on via partial sternotomy (PS) and were matched 2:1 to 196 patients operated on via full sternotomy (FS). Results: The procedure time was 12 min longer in the PS group (205 min vs. 192.5 min in the FS group, p = 0.002), however, cardiopulmonary bypass and aortic cross-clamp times were comparable between groups. Eight PS-procedures were converted to full sternotomy, predominantly for bleeding complications (n = 6). Re-exploration for acute bleeding was necessary in 11% of the PS group and 4.1% of the FS group (p = 0.02). Five FS patients and none in the PS group required emergency coronary bypass grafting for postoperative coronary obstruction (p = 0.2). PS patients were hospitalized for a significantly shorter period (9.5 days vs. 10.5 days in the FS group, respectively). There were no significant differences regarding in-hospital (p = 0.4) and mid-term mortality (p = 0.73), as well as for other perioperative complications. Conclusions: Performing Bentall operations via partial upper sternotomy is associated with similar perfusion and cross-clamp times, as well as overall mortality, when compared to a full sternotomy approach. A low threshold for conversion to full sternotomy should be accepted if limited access proves insufficient for the handling of intraoperative complications, particularly bleeding. Full article
(This article belongs to the Special Issue Recent Advances in Modern Thoracic Surgery)
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Review

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25 pages, 377 KiB  
Review
Hemoadsorption in Organ Preservation and Transplantation: A Narrative Review
by Refugio García-Villegas and Stephan Arni
Life 2024, 14(1), 65; https://doi.org/10.3390/life14010065 - 29 Dec 2023
Cited by 1 | Viewed by 877
Abstract
Cytokine adsorption can resolve different complications characteristic of transplantation medicine, such as cytokine storm activation and blood ABO and immune incompatibilities. Cytokine adsorption is also performed for the treatment of various life-threatening conditions, such as endotoxic septic shock, acute respiratory distress syndrome, and [...] Read more.
Cytokine adsorption can resolve different complications characteristic of transplantation medicine, such as cytokine storm activation and blood ABO and immune incompatibilities. Cytokine adsorption is also performed for the treatment of various life-threatening conditions, such as endotoxic septic shock, acute respiratory distress syndrome, and cardiogenic shock, all potentially leading to adverse clinical outcomes during transplantation. After surgery, dysmetabolism and stress response limit successful graft survival and can lead to primary or secondary graft dysfunction. In this clinical context, and given that a major problem in transplant medicine is that the demand for organs far exceeds the supply, a technological innovation such as a hemoadsorption system could greatly contribute to increasing the number of usable organ donors. The objectives of this review are to describe the specific advantages and disadvantages of the application of cytokine adsorption in the context of transplantation and examine, before and/or after organ transplantation, the benefits of the addition of a cytokine adsorption therapy protocol. Full article
(This article belongs to the Special Issue Recent Advances in Modern Thoracic Surgery)
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