Epilepsy and Paroxysmal Disorders: New Insights in the Diagnosis and Treatment
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 4250
Special Issue Editors
Interests: clinical neurology; epilepsy; neuroscience; mitochondria; neuropharmacology
Special Issue Information
Dear Colleagues,
Epilepsy is one of the most common neurological disorders worldwide, with a prevalence of 0.5–1% in the general population. It is a chronic dynamic medical problem that often requires long-term antiepileptic drug (AED) therapy. Of note is seizures in many patients do not remit despite appropriate medication, and lifelong AED therapy is usually required for those with refractory epilepsy. Nonepileptic paroxysmal disorders, such as sleep disorders, nocturnal movement disorders, vasovagal syncope, paroxysmal dyskinesia, episodic ataxia, tics, panic disorder, and psychogenic non-epileptic events that may result in loss of awareness, spasms, involuntary movement, limb convulsions and abrupt physical dysfunction. In semiology, these signs and symptoms may resemble epileptic seizures. Both epilepsy and paroxysmal disorders can occur unexpectedly and impact on patients’ quality of life. Differential diagnosis between epilepsy and paroxysmal disorders represents a significant challenge for the clinical physician. Meanwhile, autoimmune encephalitis may cause refractory status epilepticus and uncontrolled movement disorder. Recent discovery of novel gene mutations in ion channels indicates episodic movement disorders which frequently associates with nonepileptic paroxysmal dyskinesias and epileptic seizures. Thus, carefully diagnosis between the epileptic and nonepileptic spectrum of these diseases will help us to develop accurate and new insight of treatment. This Special Issue is open for submissions of research papers and review articles on topics including clinical and basic studies. It will focus on, but not limited to: the clinical manifestations, newly diagnostic and therapeutic strategies, biomarkers, and molecular and genetic diagnosis in epilepsy and paroxysmal disorders.
Prof. Dr. Yao-Chung Chuang
Dr. Rou-Shayn Chen
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- epilepsy
- seizure disorder
- status epilepticus
- paroxysmal disorder
- sleep disorder
- movement disorder
- antiepileptic drug
- gene mutation
- biomarker
- electrophysiology
