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Life
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Advances in Bacterial Metabolism, Gene Regulation, and Pathogenesis–Volume II
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Advances in Bacterial Metabolism, Gene Regulation, and Pathogenesis–Volume II

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Microbiology".

Deadline for manuscript submissions: closed (24 March 2023) | Viewed by 3120

Special Issue Editor

Dr. Cheng-Yen Kao

E-Mail Website
Guest Editor
Institute Microbiology and Immunology, National Yang Ming Chiao Tung University, Taipei 112, Taiwan
Interests: antibiotic resistance; bacterial genomics; bacterial pathogenesis; drug development; gene regulation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The first volume of this Special Issue was a great success; therefore, we invite you to publish your research in the second volume of this Special Issue (https://www.mdpi.com/journal/life/special_issues/Bacterial_Metabolism).

Bacterial factors such as flagella, pili, adhesins, siderophores, and toxins are critical for pathogenesis and disease development. In addition, the bacterial stress response enables these organisms to survive fluctuating conditions in their immediate surroundings, which also contributes to bacterial adaptation and persistence in the host. Various bacterial mechanisms and signaling systems recognize different environmental changes, modulate metabolism pathways and gene expression, and mount an appropriate response. Research on virulence factors and stress response has not only increased our understanding of the mechanisms underlying bacterial pathogenesis, but has also contributed to identifying novel targets for alternative antibacterial therapy. Therefore, in this Special Issue of Life, we invite researchers to submit their papers to share advances in the understanding of bacterial metabolism, gene regulation, and pathogenesis. This Special Issue will comprise the topics below:

  • Metabolomics analysis;
  • Transcriptome analysis of the pathogen;
  • Gene regulation of virulence factors;
  • Chemotaxis and motility;
  • Cell adhesion;
  • Signal transduction;
  • Stress response;
  • Toxin production and secretion;
  • Immune evasion mechanisms.

Dr. Cheng-Yen Kao
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metabolomics analysis
  • transcriptome analysis of the pathogen
  • gene regulation of virulence factors
  • chemotaxis and motility
  • cell adhesion
  • signal transduction
  • stress response
  • toxin production and secretion
  • immune evasion mechanisms

Published Papers (2 papers)

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Research

16 pages, 2637 KiB  
Article
Phenanthrene Degradation by Photosynthetic Bacterial Consortium Dominated by Fischerella sp.
by José Martín Márquez-Villa, Juan Carlos Rodríguez-Sierra, Nayem Amtanus Chequer, Nubia Noemí Cob-Calan, José Quinatzín García-Maldonado, Santiago Cadena and Emanuel Hernández-Núñez
Life 2023, 13(5), 1108; https://doi.org/10.3390/life13051108 - 28 Apr 2023
Viewed by 1574
Abstract
Microbial degradation of aromatic hydrocarbons is an emerging technology, and it is well recognized for its economic methods, efficiency, and safety; however, its exploration is still scarce and greater emphasis on cyanobacteria–bacterial mutualistic interactions is needed. We evaluated and characterized the phenanthrene biodegradation [...] Read more.
Microbial degradation of aromatic hydrocarbons is an emerging technology, and it is well recognized for its economic methods, efficiency, and safety; however, its exploration is still scarce and greater emphasis on cyanobacteria–bacterial mutualistic interactions is needed. We evaluated and characterized the phenanthrene biodegradation capacity of consortium dominated by Fischerella sp. under holoxenic conditions with aerobic heterotrophic bacteria and their molecular identification through 16S rRNA Illumina sequencing. Results indicated that our microbial consortium can degrade up to 92% of phenanthrene in five days. Bioinformatic analyses revealed that consortium was dominated by Fischerella sp., however different members of Nostocaceae and Weeksellaceae, as well as several other bacteria, such as Chryseobacterium, and Porphyrobacter, were found to be putatively involved in the biological degradation of phenanthrene. This work contributes to a better understanding of biodegradation of phenanthrene by cyanobacteria and identify the microbial diversity related. Full article
(This article belongs to the Special Issue Advances in Bacterial Metabolism, Gene Regulation, and Pathogenesis–Volume II)
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18 pages, 3029 KiB  
Article
Study of the Effectiveness of Alumina and HDTMA/Alumina Composite in the Removal of Para-Nitrophenol and the Deactivation of Bacterial Effect of Listeria monocytogenes and Salmonella spp.
by Mustapha Aazza, Chadia Mounir, Hammou Ahlafi, Hamou Moussout, Aziz Bouymajane, Mounia Chroho, Filippo Giarratana, Luca Nalbone and Francesco Cacciola
Life 2022, 12(11), 1700; https://doi.org/10.3390/life12111700 - 26 Oct 2022
Cited by 2 | Viewed by 1179
Abstract
Removal of para-nitrophenol (p-NP) from an aqueous solution was studied under various batch adsorption experiments, using alumina (Al2O3) and its composite hexadecyltrimethylammonium bromide (HDTMA+-Br−) as adsorbents. These were later characterized, before and after adsorption of [...] Read more.
Removal of para-nitrophenol (p-NP) from an aqueous solution was studied under various batch adsorption experiments, using alumina (Al2O3) and its composite hexadecyltrimethylammonium bromide (HDTMA+-Br−) as adsorbents. These were later characterized, before and after adsorption of p-NP, by thermal analysis (DSC-TG), X-ray diffraction (XRD), Fourier transform infrared (FTIR), and UV/Visible spectroscopies. The results show that HDTMA+/Al2O3 adsorbents have a greater affinity toward p-NP than Al2O3 alone. Linear and non-linear forms of kinetics and isotherms were used to analyze the experimental data obtained at different concentrations and temperatures. The results indicate that the pseudo-second order kinetic model provided the best fit to the experimental data for the adsorption of p-NP on both adsorbents, and that the intra-particle diffusion was not only the rate controlling step. Both the Langmuir and Redlich-Peterson (R-P) models were found to fit the sorption isotherm data well, but the Langmuir model was better. Physical adsorption of p-NP onto the adsorbents proved to be an endothermic and spontaneous process at high temperatures, which mainly involves a hydrogen bonding mechanism of interactions between p-NP and functional groups of adsorbents. The antibacterial activity of Al2O3, HDTMA+-Br− and HDTMA+/Al2O3 were evaluated against Listeria monocytogenes and Salmonella spp. strains using both disc diffusion and broth microdilution methods. The HDTMA+-Br− and HDTMA+/Al2O3 displayed a bacteriostatic effect against all tested strains of Listeria monocytogenes and Salmonella spp., while Al2O3 exhibited no bacterial effect against all bacterial strains tested. Full article
(This article belongs to the Special Issue Advances in Bacterial Metabolism, Gene Regulation, and Pathogenesis–Volume II)
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