Research Advances in Eukaryotic Pan-Genomics
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Genetics and Genomics".
Deadline for manuscript submissions: closed (30 January 2023) | Viewed by 2357
Special Issue Editors
Interests: pan-genome; genomic privacy; personal genome; genetic variant impact; functional genomics
Interests: molecular breeding in rice; abiotic tolerance; GWAS; plant genetics and genomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The use of species’ reference genomes has shaped methodologies in modern genomics. However, a single reference genome does not capture all of the genome content of a species. A pan-genome analysis, which aims to reveal a species’ entire genome content, has recently been applied to higher eukaryotes, including crops and humans. However, significant bottlenecks still block our understanding and application of a pan-genome. For example, using a pan-genome in the same way as using a single reference genome for sequence-based analyses is still very challenging. In addition, due to the customized parameters involved in pan-genome construction, pan-genome characteristics reported for the same or different species are not comparable.
In this Special Issue, we aim to provide a platform for original research and literature reviews broadly related to human and plant pan-genomes, including, but not limited to, the development and assessment of relevant tools, pan-genome analyses of public or newly generated data, comparisons of pan-genome characteristics across species, and applications where a pan-genome brings novel insights (e.g., a genome-wide association analysis based on a pan-genome).
Dr. Zhiqiang Hu
Dr. Fan Zhang
Guest Editors
Manuscript Submission Information
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Keywords
- pan-genome
- pangenome
- eukaryotic pan-genome
- population genetics
- presence-absence variation
- comparative genomics
