Effects of Exercise Training on Muscle Function

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 26 August 2024 | Viewed by 1553

Special Issue Editors

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Guest Editor
Department of Sport, Exercise, Recreation, and Kinesiology, Clemmer College, East Tennessee State University, Johnson City, TN 37614, USA
Interests: resistance training; football; track and field; sprint; strength and conditioning

Special Issue Information

Dear Colleagues,

We are excited to introduce the Special Issue titled "Effects of Exercise Training on Muscle Function", dedicated to advancing our understanding of the impacts of exercise, with a focus on resistance training and high-intensity interval training (HIIT), on muscle function in sports and trained individuals.

Exercise training has emerged as a vital tool in optimizing athletic performance and overall fitness. This Special Issue seeks to unravel the intricate mechanisms underlying how these training modalities influence muscle function at various levels.

Resistance training, characterized by progressively challenging muscular contractions, has shown the capacity to induce muscle hypertrophy, enhance strength, and improve functional abilities. Similarly, HIIT, involving brief bursts of intense exercise followed by recovery periods, has gained attention for its potential to boost cardiovascular fitness and metabolic efficiency, potentially affecting muscle fibre composition.

Through a collection of research articles and reviews, this Special Issue aims to provide a comprehensive exploration of the effects of resistance training and HIIT on muscle function. We invite submissions elucidating the molecular, cellular, and physiological adaptations that drive these improvements. Additionally, we encourage investigations into their integration within sports training and protocols, as well as potential synergies between these modalities.

This Special Issue serves as a platform to enrich our understanding of how exercise training influences muscle function, providing invaluable insights for both practitioners and researchers.

Together, let us bridge the gap between theory and practice, fostering a deeper comprehension of how these training modalities can optimize muscle function and ultimately elevate physical performance.

Dr. Marco Duca
Dr. Athos Trecroci
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • exercise
  • training
  • muscle function
  • resistance training
  • HIIT

Published Papers (1 paper)

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15 pages, 1830 KiB  
Management of Upper-Limb Spasticity Using Modern Rehabilitation Techniques versus Botulinum Toxin Injections Following Stroke
by Ana Maria Bumbea, Otilia Constantina Rogoveanu, Adina Turcu-Stiolica, Ionica Pirici, George Cioroianu, Diana Iulia Stanca, Oana Criciotoiu, Viorel Biciusca, Rodica Magdalena Traistaru and Danut Visarion Caimac
Life 2023, 13(11), 2218; https://doi.org/10.3390/life13112218 - 17 Nov 2023
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Our purpose is to emphasize the role of botulinum toxin in spasticity therapy and functional recovery in patients following strokes. Our retrospective study compared two groups, namely ischemic and hemorrhagic stroke patients. The study group (BT group) comprised 80 patients who received focal [...] Read more.
Our purpose is to emphasize the role of botulinum toxin in spasticity therapy and functional recovery in patients following strokes. Our retrospective study compared two groups, namely ischemic and hemorrhagic stroke patients. The study group (BT group) comprised 80 patients who received focal botulinum toxin as therapy for an upper limb with spastic muscle three times every three months. The control group (ES group) comprised 80 patients who received only medical rehabilitation consisting of electrostimulation and radial shockwave therapy for the upper limb, which was applied three times every three months. Both groups received the same stretching program for spastic muscles as a home training program. We evaluated the evolution of the patients using muscle strength, Ashworth, Tardieu, Frenchay, and Barthel scales. The analysis indicated a statistically significant difference between the two groups for all scales, with better results for the BT group (p < 0.0001 for all scales). In our study, the age at disease onset was an important prediction factor for better recovery in both groups but not in all scales. Better recovery was obtained for younger patients (in the BT group, MRC scale: rho = −0.609, p-value < 0.0001; Tardieu scale: rho = −0.365, p-value = 0.001; in the ES group, MRC scale: rho = −0.445, p-value < 0.0001; Barthel scale: rho = −0.239, p-value = 0.033). Our results demonstrated the effectiveness of botulinum toxin therapy compared with the rehabilitation method, showing a reduction of the recovery time of the upper limb, as well as an improvement of functionality and a reduction of disability. Although all patients followed a specific kinetic program, important improvements were evident in the botulinum toxin group. Full article
(This article belongs to the Special Issue Effects of Exercise Training on Muscle Function)
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