Molecular Genetics and Genomics of Mushroom-Forming Fungi, 2nd Edition

A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Genomics, Genetics and Molecular Biology".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 2080

Special Issue Editor


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Guest Editor
School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China
Interests: mushroom genomics; fungal evolution; molecular genetics of mushrooms; population genomics of mushrooms; fungal pathogens of trees
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Special Issue Information

Dear Colleagues,

The Special Issue of “Molecular Genetics and Genomics of Mushroom-forming Fungi” was very successful. The Journal of Fungi decided to publish a second edition of the Special Issue. The second edition has now been re-opened to invite more contributions to the topic. I am again pleased to invite you to submit your invaluable contributions to this Special Issue of “Molecular Genetics and Genomics of Mushroom-forming Fungi, Second Edition”. This Special Issue is a great opportunity for us who share our passions in the study of mushrooms to publish our recent achievements together in one issue of this excellent journal. Mushroom-forming fungi provide great models for the study of fungal development, differentiation, genetic regulation, morphogenesis, and evolution. We have all been fascinated by the complex structure produced from microscopic mycelium. The conspicuous structures of mushrooms and related sclerotia are subjects with relative ease to investigate various biological processes in the fungal life cycle. However, even though we have been using mushrooms as food and medicine for thousands of years to our benefit, many of them are not well understood in terms of their basic biology and genetics. Not until the early 1990’s, when molecular genetic technology advanced to be applicable for the study of living organisms with less-known basic genetics and genetic tools, that the molecular genetic studies of mushrooms really took off. The advances in genomic technology as a result of the human genome project further allowed more in-depth analyses of mushroom gene regulation, genetic structure, development, and evolution. Now that advanced molecular genetic and genomic tools have matured, we can really start to gain a good understanding of mushroom biology. The scope of the studies has expanded from single gene to whole genome studies, and from model mushrooms to those with nutritional, medicinal, and environmental values.

I encourage you to join us in showcasing our recent achievements in molecular genetics and genomics of mushroom-forming fungi in the second edition of this Special Issue. This would serve as a landmark of the high level of science in this extraordinarily interesting field.

Prof. Dr. Hoi Shan Shan Kwan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • mushrooms
  • genomics
  • population genomics
  • DNA sequencing
  • RNA sequencing
  • transcriptomics
  • epigenomics
  • phylogeny
  • evolution
  • multicellularity
  • mating types
  • genetic architecture
  • fruiting body development
  • CRISPR

Published Papers (1 paper)

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Research

20 pages, 9897 KiB  
Article
Comparative Genomic Analysis and Metabolic Potential Profiling of a Novel Culinary-Medicinal Mushroom, Hericium rajendrae (Basidiomycota)
by Jing Wei, Min Cheng, Jian-fang Zhu, Yilin Zhang, Kun Cui, Xuejun Wang and Jianzhao Qi
J. Fungi 2023, 9(10), 1018; https://doi.org/10.3390/jof9101018 - 15 Oct 2023
Cited by 2 | Viewed by 1747
Abstract
Hericium rajendrae is an emerging species in the genus Hericium with few members. Despite being highly regarded due to its rarity, knowledge about H. rajendrae remains limited. In this study, we sequenced, de novo assembled, and annotated the complete genome of H. rajendrae [...] Read more.
Hericium rajendrae is an emerging species in the genus Hericium with few members. Despite being highly regarded due to its rarity, knowledge about H. rajendrae remains limited. In this study, we sequenced, de novo assembled, and annotated the complete genome of H. rajendrae NPCB A08, isolated from the Qinling Mountains in Shaanxi, China, using the Illumina NovaSeq and Nanopore PromethION technologies. Comparative genomic analysis revealed similarities and differences among the genomes of H. rajendrae, H. erinaceus, and H. coralloides. Phylogenomic analysis revealed the divergence time of the Hericium genus, while transposon analysis revealed evolutionary characteristics of the genus. Gene family variation reflected the expansion and contraction of orthologous genes among Hericium species. Based on genomic bioinformation, we identified the candidate genes associated with the mating system, carbohydrate-active enzymes, and secondary metabolite biosynthesis. Furthermore, metabolite profiling and comparative gene clusters analysis provided strong evidence for the biosynthetic pathway of erinacines in H. rajendrae. This work provides the genome of H. rajendrae for the first time, and enriches the genomic content of the genus Hericium. These findings also facilitate the application of H. rajendrae in complementary drug research and functional food manufacturing, advancing the field of pharmaceutical and functional food production involving H. rajendrae. Full article
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