New Discovery on Antifungal Drugs

A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Pathogenesis and Disease Control".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 862

Special Issue Editor


E-Mail Website
Guest Editor
Sobresp Faculty of Health Sciences, Santa Maria, RS, Brazil
Interests: antifungal susceptibility; fungal identification methods; Pythium insidiosum; experimental models of infections

Special Issue Information

Dear Colleagues,

The Journal of Fungi is announcing a Special Issue dedicated to "New Discoveries on Antifungal Drugs", as the rising incidence of fungal infections and increasing resistance to existing treatments, such as the emerging forms of Candida auris that are multiresistant to antifungal drugs, demand innovative approaches. This Special Issue will feature research and review manuscripts on recent advances in antifungal drugs and strategies. These include introducing novel antifungal drugs, strategies employing combination therapy to overcome fungal resistance, and the potential for repurposing drugs with antifungal activity against pathogenic fungi. Furthermore, we invite submissions investigating the challenges associated with fungal resistance and novel techniques developed for evaluating the susceptibility of pathogenic fungi. Understanding the mechanisms of antifungal resistance is also within the scope of this Special Issue. Together, these contributions will provide crucial insights into innovative strategies for overcoming resistance and novel methods for evaluating fungal susceptibility, thereby addressing the growing threat of antifungal resistance.

Dr. Erico Silva De Loreto
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antifungal resistance mechanisms
  • combination therapy
  • drug repurposing
  • emerging resistance
  • fungal susceptibility
  • novel antifungal drugs

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

21 pages, 3357 KiB  
Review
Treating Pythiosis with Antibacterial Drugs Targeting Protein Synthesis: An Overview
by Erico S. Loreto, Juliana S. M. Tondolo and Régis A. Zanette
J. Fungi 2024, 10(4), 234; https://doi.org/10.3390/jof10040234 - 22 Mar 2024
Viewed by 675
Abstract
This review article explores the effectiveness of antibacterial drugs that inhibit protein synthesis in treating pythiosis, a difficult-to-treat infection caused by Pythium insidiosum. The article highlights the susceptibility of P. insidiosum to antibacterial drugs, such as macrolides, oxazolidinones, and tetracyclines. We examine [...] Read more.
This review article explores the effectiveness of antibacterial drugs that inhibit protein synthesis in treating pythiosis, a difficult-to-treat infection caused by Pythium insidiosum. The article highlights the susceptibility of P. insidiosum to antibacterial drugs, such as macrolides, oxazolidinones, and tetracyclines. We examine various studies, including in vitro tests, experimental infection models, and clinical case reports. Based on our synthesis of these findings, we highlight the potential of these drugs in managing pythiosis, primarily when combined with surgical interventions. The review emphasizes the need for personalized treatment strategies and further research to establish standardized testing protocols and optimize therapeutic approaches. Full article
(This article belongs to the Special Issue New Discovery on Antifungal Drugs)
Show Figures

Figure 1

Back to TopTop