Special Issue "Current Challenges and Advances in Atherosclerosis"
Deadline for manuscript submissions: 25 February 2024 | Viewed by 25281
A printed edition of this Special Issue is available here.
Interests: atherosclerosis; inflammation; antigen; antibodies; auto-antibodies; interleukin 5; B1 cell; B2 cell; spleen; tertiary lymphoid tissue
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Atherosclerosis is a phenomenon which is of major interest in both basic science and clinical medicine in order to achieve healthy longevity worldwide. Atherosclerosis generally develops without any signs and symptoms, eventually resulting in various kinds of catastrophic cardiovascular events, such as ischemic heart disease, ischemic stroke, and rupture of major vessel aneurysm. Scientists working on the biological aspects of atherosclerosis have recently focused on the inflammation seen in vessel walls from intimal to adventitial tissues. However, although inflammation is indeed a dominant pathological phenomenon in atherosclerosis, it has been recognized that there is no simple answer to the question of whether inflammation promotes or retards atherosclerosis. Atherosclerosis is a complex disease that involves several different cell types, such as lymphocytes, macrophages, monocytes, dendric cells, and their molecular products. Chronic inflammation in atherosclerosis might be accompanied with basical immunological changes, including auto-immune disorders. For example, recent studies have shown that multiple auto-antibodies are found in the sera of the subjects with atherosclerosis via inventory high-throughput auto-antibody screening techniques using cell-free technologies. Nevertheless, the immune system is even more complicated, with many cell types, hundreds of cytokines, and literally millions of different antigens. This Special Issue, titled “Current Challenges and Advances in Atherosclerosis”, will focus on recent challenges and advances in the field of atherosclerosis by global expert scientists and clinicians to elucidate the complicated features of atherosclerosis and translational attempts for medical–clinical frontiers.
Dr. Tomoaki Ishigami
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- B cell
- T cell
- tertiary lymphoid tissue