Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.4
3.9
Journals
JCM
Special Issues
Current Challenges and Management of Substance Use Disorders and Other...
share announcement

Current Challenges and Management of Substance Use Disorders and Other Mental Health Problems

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Mental Health".

Deadline for manuscript submissions: 25 July 2024 | Viewed by 1739

Special Issue Editor

Dr. Ainhoa Bilbao

E-Mail Website
Guest Editor
1. Animal Facility and Animal Experimentation Unit, Biocruces Bizkaia Health Reseach Institute, 48903 Barakaldo, Spain
2. Central Institute of Mental Health, Faculty of Medicine Mannheim, University of Heidelberg, 68159 Mannheim, Germany
Interests: reward learning; mental health; addictions; behavioral genetics; cannabinoid system
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Substance use disorders and mental health problems are influenced by complex and often common social, lifestyle, behavioral and genetic factors. Indeed, mental health problems can result in a substance use disorder by increased exposure to drugs due to behavioral alterations (i.e., impulse control, mood alterations), and substance use disorders can lead to the development of mental health problems as a consequence of drug-induced neuropsychobiological alterations.

At an interventional level, the treatment and management of patients with co-occurring addiction and mental health problems is very challenging ¦usually resulting in negative impact treatment outcomes due to the more severe phenotype of the patients (chronic and treatment-resistant) and the lack of integration in addiction and mental health treatment settings. To fill this gap, it is critically important to gain a better understanding of the multiple interactions between genetic, biological and environmental aspects leading to the co-occurrence of both disorders and to strengthen integrative, multidisciplinary clinical settings.

This Special Issue intends to bring together experts on substance use disorders and other metal health problems addressing all these aspects. We encourage submissions of original research or review articles that highlight the current progress, gaps in the field and future challenges, thereby promoting novel research in this topic.

Dr. Ainhoa Bilbao
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • addiction
  • mental health
  • humans
  • treatment
  • comorbidities
  • intervention
  • management

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Other

25 pages, 1166 KiB  
Article
Effects of a Two-Month Exercise Training Program on Concurrent Non-Opiate Substance Use in Opioid-Dependent Patients during Substitution Treatment
by Alexandros Psarianos, Costas Chryssanthopoulos, Athanasios Theocharis, Thomas Paparrigopoulos and Anastassios Philippou
J. Clin. Med. 2024, 13(4), 941; https://doi.org/10.3390/jcm13040941 - 06 Feb 2024
Viewed by 737
Abstract
Background: This randomized controlled trial aimed to evaluate the effects of a two-month exercise intervention on the concurrent non-opiate substance use (alcohol, cocaine, cannabis, and benzodiazepines) in opioid users during their medication treatment. Methods: Ninety opioid users (41 females) in methadone and buprenorphine [...] Read more.
Background: This randomized controlled trial aimed to evaluate the effects of a two-month exercise intervention on the concurrent non-opiate substance use (alcohol, cocaine, cannabis, and benzodiazepines) in opioid users during their medication treatment. Methods: Ninety opioid users (41 females) in methadone and buprenorphine medication treatment were randomly divided into four groups: (a) buprenorphine experimental (BEX; n = 26, aged 41.9 ± 6.1 yrs); (b) buprenorphine control (BCON; n = 25, aged 41.9 ± 5.6 yrs); (c) methadone experimental (MEX; n = 20, aged 46.7 ± 6.6 yrs); and (d) methadone control (MCON; n = 19, aged 46.1 ± 7.5 yrs). The experimental groups (BEX and MEX) followed an aerobic exercise training program on a treadmill for 20 min at 70% HRmax, 3 days/week for 8 weeks. Socio-demographic, anthropometric, and clinical characteristics, as well as non-opioid drug use in days and quantity per week, were assessed before and after the intervention period. Results: Following the exercise training, the weekly non-opioid substance consumption (days) decreased (p < 0.05) in both exercise groups and was lower in BEX compared to MEX, while no differences were observed (p > 0.05) between the control groups (BCON vs. MCON) or compared to their baseline levels. Similarly, the daily amount of non-opiate substance intake was reduced (p < 0.05) post-training in BEX and MEX, whereas it did not differ (p > 0.05) in BCON and MCON compared to the baseline. Conclusions: The two-month exercise intervention reduced the non-opioid drug use in both the methadone and buprenorphine substitution groups compared to the controls, suggesting that aerobic exercise training may be an effective strategy for treating patients with OUDs. Full article
(This article belongs to the Special Issue Current Challenges and Management of Substance Use Disorders and Other Mental Health Problems)
►▼ Show Figures

Graphical abstract

Other

Jump to: Research

14 pages, 950 KiB  
Systematic Review
Cardiovascular Risks of Simultaneous Use of Alcohol and Cocaine—A Systematic Review
by Jan van Amsterdam, Femke Gresnigt and Wim van den Brink
J. Clin. Med. 2024, 13(5), 1475; https://doi.org/10.3390/jcm13051475 - 04 Mar 2024
Viewed by 631
Abstract
Background: The simultaneous use of cocaine and alcohol is highly prevalent and is associated with high numbers of emergency department admissions, primarily due to cardiovascular complications. Aims: To answer the question of whether the co-use of cocaine and alcohol increases the cardiovascular [...] Read more.
Background: The simultaneous use of cocaine and alcohol is highly prevalent and is associated with high numbers of emergency department admissions, primarily due to cardiovascular complications. Aims: To answer the question of whether the co-use of cocaine and alcohol increases the cardiovascular risk compared to the use of cocaine alone. Method: A systematic review of human studies comparing the cardiovascular risk of co-used cocaine and alcohol with the use of cocaine alone. Results: Despite a higher myocardial workload induced by the co-use of cocaine and alcohol and the potentiation of cocaine’s cardiovascular effects by alcohol, the findings on the risk and severity of cardiovascular symptoms due to combined use are inconsistent. However, the co-use of cocaine and alcohol clearly leads to higher mortality. Interestingly, the presence of cocaethylene, a unique metabolite generated only via a pharmacokinetic interaction between alcohol and cocaine, carries an 18- to 25-fold increase over the absence of cocaethylene (cocaine-alone users) in the risk of sudden death and is associated with myocardial injury and cardiac arrest, probably due to the inhibition of cardiac ion channels by cocaethylene. Conclusion: Despite the inconsistency in some of the results, it is concluded that the co-use of cocaine and alcohol poses an additional risk of cardiovascular fatalities compared to the use of cocaine alone. Full article
(This article belongs to the Special Issue Current Challenges and Management of Substance Use Disorders and Other Mental Health Problems)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop