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Retinal Imaging: Clinical Applications, Updates and Perspectives
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Retinal Imaging: Clinical Applications, Updates and Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 15 June 2024 | Viewed by 1129

Special Issue Editors

Dr. Andreas Pollreisz

E-Mail Website
Guest Editor
Department of Ophthalmology and Optometry, Medical University Vienna, 1090 Vienna, Austria
Interests: widefield OCT; adaptive optics OCT; diabetic retinopathy; age-related macular degeneration; multimodal imaging; minimally invasive vitreoretinal surgery; retinal pigment epithelium
Dr. Thomas Ach

E-Mail Website
Guest Editor
Department of Ophthalmology, University Hospital Bonn, 53127 Bonn, Germany
Interests: fundus autofluorescence; quantitative fundus autofluorescence; optical coherence tomography; age-related macular degeneration; diabetic retinopathy; chloroquine maculopathy; multimodal imaging; retinal pigment epithelium; minimally invasive retinal surgery

Special Issue Information

Dear Colleagues,

Retinal imaging is essential for the diagnosis, monitoring and treatment decisions of retinal diseases. Currently, there are a number of imaging modalities available, including optical coherence tomography (OCT), OCT angiography, autofluorescence, widefield color fundus/fluorescein/indocyanine green imaging or adaptive optics-assisted imaging (OCT, scanning laser ophthalmoscope). These cutting-edge technologies allow the visualization of a wide range of different aspects of the retina from a scale where individual cells are visible up to the depiction of a large field of views covering retinal areas even in the far periphery. Some of these novel imaging systems still require clinical validation to prove their applicability in routine clinical practice, particularly with new treatment modalities on the horizon. The ultimate goal of these imaging advancements is to positively support the clinician’s approach for diagnosing and treating various vitreoretinal diseases, including diabetic retinopathy, age-related macular degeneration, retinal vessel occlusions, retinal detachment, uveitis, retinal dystrophies and others.

The aim of this Special Issue is to highlight recent advancements in any aspects of retinal imaging in the form of original contributions and reviews.

Dr. Andreas Pollreisz
Dr. Thomas Ach
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • optical coherence tomography
  • widefield imaging
  • adaptive optics-assisted imaging
  • retinal diseases
  • fundus autofluorescence
  • quantitative fundus autofluorescence

Published Papers (1 paper)

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Research

10 pages, 2080 KiB  
Article
Macular Microvascular Perfusion Status in Hypertensive Patients with Chronic Kidney Disease
by Heiko Stino, Elisa de Llano Pato, Irene Steiner, Nikolaus Mahnert, Maximilian Pawloff, Matthias Hasun, Franz Weidinger, Ursula Schmidt-Erfurth and Andreas Pollreisz
J. Clin. Med. 2023, 12(17), 5493; https://doi.org/10.3390/jcm12175493 - 24 Aug 2023
Cited by 1 | Viewed by 887
Abstract
To compare retinal microvascular perfusion between the eyes of hypertensive patients with and without chronic kidney disease (CKD), the vessel density (VD) and fractal dimension (FD) of the superficial (SVP) and deep retinal vascular plexus (DVP) were analyzed on 6 × 6 mm [...] Read more.
To compare retinal microvascular perfusion between the eyes of hypertensive patients with and without chronic kidney disease (CKD), the vessel density (VD) and fractal dimension (FD) of the superficial (SVP) and deep retinal vascular plexus (DVP) were analyzed on 6 × 6 mm fovea-centered optical coherence tomography angiography (OCTA) images of patients with hypertension. The retina was divided into an inner ring (IR) and outer ring (OR) according to the Early Treatment of Diabetic Retinopathy Study grid. The glomerular filtration rate (GFR) was determined and CKD was diagnosed (GFR < 60 mL/min/1.73 m2). Ninety-six eyes from 52 patients with hypertension were included in this analysis. Twenty patients (n = 37 eyes) were diagnosed with CKD. The mean age was 69 ± 11.7 years and 60.4 ± 9.2 years in the CKD group and in the control group, respectively. The univariate model revealed a significant difference in VD between patients without and with CKD in the superficial IR (0.36 ± 0.03 vs. 0.34 ± 0.04, p = 0.03), the superficial OR (0.35 ± 0.02 vs. 0.33 ± 0.04, p = 0.02), the deep OR (0.24 ± 0.01 vs. 0.23 ± 0.02, p = 0.003), and the FD in the SVP (1.87 ± 0.01 vs. 1.86 ± 0.02, p = 0.02) and DVP (1.83 ± 0.01 vs. 1.82 ± 0.01, p = 0.006). After adjusting for age and sex, these differences did not remain statistically significant. Similar results were observed for the FD in the SVP and DVP. In our cohort, patients with hypertension and CKD did not differ from patients without CKD in regard to microvascular perfusion status in the macular area as assessed using OCTA. Full article
(This article belongs to the Special Issue Retinal Imaging: Clinical Applications, Updates and Perspectives)
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