Transcription Factors in Plant Gene Expression Regulation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 525
Special Issue Editor
Interests: medicinal plant molecular biology; medicinal plant genetics; promoter structure and function; plant secondary metabolites; protein homology modeling
Special Issue Information
Dear Colleagues,
Plant transcription factors play a decisive role in the regulation of gene expression. Their interactions with promoter and enhancer regions are pivotal for the building of the RNA polymerase preinitiation complex. The activation and degradation of plant trans-factors are precisely regulated by post-translational modifications in response to diverse events occurring within plant cells or outside of the plant body as biotic or abiotic stress factors. The plant trans-factors interact with oligo DNA sequences known as cis-active elements. Although the position weight matrices for plant cis-active elements are characterized in plentiful databases, the binding of trans-factors in in vivo conditions is dependent on interactions that are often imperfect, weak, and protein- or DNA modification-dependent. Numerous trans-factors require to undergo dimerization or oligomerization to achieve their active state, adding another control stratum to gene expression regulation. Building functional dimers or oligomers of trans-factors may be dependent on the closely localized cis-elements confined within the promoter sequence. Usually, cis-active elements that are important for gene regulation are not distributed statistically but concentrated within evolutionary conserved promoter fragments known as modules. Original research and reviews articles from experts in the field are welcome.
Dr. Piotr Szymczyk
Guest Editor
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Keywords
- plant trans-factor
- cis-active sequence
- post-translational modification
- dimerization and oligomerization
- DNA modules
