Special Issue "Recent Advances in the Pathobiology of Diabetes Mellitus and Its Complications"
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 4463
Interests: essential fatty acids; eicosanoids; cytokines; free radicals; nitric oxide; melatonin and their role in various clinical conditions
Special Issues, Collections and Topics in MDPI journals
Several diseases, including cancer, radiation-induced damage and its usefulness in cancer therapy, metabolic syndrome (inclduing obesity, diabetes mellitus, hypertension, cadiovascular diseases), Alzheimer‘ disease, COVID-19 infection and its complications suchas ARDS, sepsis, multiple sclerosis, and other diseases, all have inflammation and altered immune system as the underlying mechanism(s) in their pathobiology and hence the keys to their prevention and management. The various factors involved in inflamamtory events and immune system dysregulation in thsese diseases include altered cytokines, reactive oxygen species, adhesion factors, T and B cell dysregulation, lipid mediators, changes in genes/oncogenes expression, cytoskeleton abnormalities, etc. Hence, it is important to understand how all these events/factors interact with each other and what these interaction(s) mean for various physiological and pathological processes and diseases. This implies that we need to develop a comprehensive understanding of various cellular events and processes pertaining to inflammation, anti-inflammation, immune response and its regulation and dysregulation, wound healing, and the restoration of homeostasis. This Special Issue focusses on such events and cellular processes. We coordially invite all scientists/physicians/cell biologists and others who wish to develop a comprehensive view of physiology and pathology in a wholesome manner. Based on the development of such concepts, we anticipate and encourage all authors to develop and propose novel preventive and therapeutic approaches to various diseases—no matter how radical or unthinkable they appear to be at present. We particularly encourage authors to propose novel ideas that appear to be against the current dogma(s) (but they need to be logical, reasonable, and convincing) and how such ideas can be verified or tested also have to be suggested for others to test these ideas.
Prof. Dr. Das Undurti
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- adhesion molecules