Molecular Study and Treatment of Motor Neuron Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 28 August 2024 | Viewed by 915
Special Issue Editors
Interests: neurodegeneration; amyotrophic lateral sclerosis; RNA metabolism; RNA-binding proteins; stress response; spinal muscular atrophy; repeat expansion disorders, antisense oligonucleotides
Interests: molecular mechanisms of neurodegeneration; amyotrophic lateral sclerosis; neuroinflammation; microglia; fibrosis; astrocytes; animal models of neurodegenerative diseases; purinergic signaling; histaminergic signaling; neuropharmacology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Motor neuron diseases (MNDs) are a group of progressive neurological disorders in which motor neurons undergo degeneration and death. It includes diseases such as amyotrophic lateral sclerosis (ALS), progressive bulbar palsy (PBP), primary lateral sclerosis (PLS), progressive muscular atrophy (PMA), spinal muscular atrophy (SMA), spinal and bulbar muscular atrophy (SBMA), and post-polio syndrome.
Although recent progress in neurochemical, physiological, genetic investigations has led to the identification of several cellular processes that seem to be involved in the motor neuronal degeneration, certain questions about the pathogenic mechanisms of MNDs remain unknown. Comprehension of these underlying mechanisms is of paramount importance because it can play a crucial role in the research and development of novel therapeutic strategies.
This Special Issue invites submissions of original papers and review articles that highlight the latest discoveries and advancements in the field of pathophysiological mechanisms, biomarker research and novel therapeutic targets in MND.
Dr. Simona Rossi
Dr. Savina Apolloni
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- motor neuron
- amyotrophic lateral sclerosis
- neuronal degeneration
- pathogenic mechanisms
- molecular therapy
