Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 23250
Interests: sarcoma; chemotherapy; immunotherapy; biological reconstruction
Special Issues, Collections and Topics in MDPI journals
Due to the rarity and heterogeneity of sarcoma, investigation into molecular targets and new treatments has been particularly challenging. Although intensive chemotherapy and establishment of surgical procedures have improved the outcomes of patients with sarcomas, the curative rate of recurrent and metastatic sarcomas remains unsatisfactory. Recent basic science research has revealed some of the mechanisms of progression and metastasis of malignancies including proliferation, apoptosis, angiogenesis, tumor microenvironment, migration, invasion, and regulation of antitumor immune systems. Based on these basic studies, new anticancer drugs have been developed and the efficacies and safety of the new drugs have been assessed by clinical trials. This Special Issue aims to bring together the highest quality original/review articles on basic and clinical research for bone and soft tissue tumors. Molecular biology, microenvironment, mechanisms of metastasis, as well as articles analyzing recent clinical researches of new therapeutic approaches are invited.
Dr. Shinji Miwa
Manuscript Submission Information
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- molecular target
- clinical trial
- therapeutic target