Roles of the Immune System in Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 2830
Special Issue Editor
Interests: clinical biochemistry; leukemia and lymphoma; molecular biomarkers; immunotherapy; T- and B-cell biology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
While the inherent genetic mechanisms of early cancer cells are likely to initiate cancer development, the immune system plays a crucial role in determining the following outcomes of cancer progression. The success of new immunotherapeutic strategies demonstrates that intervention in the interplay between immune and tumor cells can positively modify an unfavorable evolution of the disease. At the same time, the real effectiveness of this intervention cannot be separated from an exhaustive understanding of the particular history of each individual tumor and its dynamic relationship with the immune system.
This Topical Collection aims to cover all fields of basic research in the study of tumor immunology. It welcomes original research, reviews, and short communication articles on the cellular and molecular mechanisms of antitumor adaptive and innate immunity, as well as the innovative biomarkers involved in predicting responses to immunotherapy in cancer. This Topical Collection welcomes papers covering, but not limited to, the following topics:
- The role of immune cells in the tumor microenvironment;
- Tumor-associated macrophages in cancer progression and response;
- Natural killer cells in cancer immunotherapy;
- Myeloid-derived suppressor cells;
- Cancer stem cells and epithelial-to-mesenchymal transition;
- Ageing and tumor immune escape;
- Chimeric antigen receptor gene therapy in cancer;
- New checkpoint inhibitor pathways;
- Identification of novel tumor antigens for clinical evaluation;
- Immune repertoire analysis and innovative biomarkers
Prof. Camillo Palmieri
Collection Editor
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