New Insights into Neurotoxicity
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 1221
Special Issue Editor
Interests: ER stress; oxidative stress; inflammation; senescence; autophagy; proteinopathies; metallopathies; channelopathies; chronic; neuroglia; vascular
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurotoxicity occurs when the exposure to natural or artificial toxic substances (termed neurotoxicants) alters the normal activity of the nervous system. This can eventually stress or potentially kill neurons crucial for transmitting and processing signals in the brain and other parts of the nervous system. Examples of neurotoxic agents include chemotherapy drugs that are used to kill rapidly growing cells, drug therapies or drugs of abuse, certain foods and food additives, insecticides/pesticides, cosmetics, radiation, industrial and cleaning solvents, and heavy metals such as vanadium, chromium, mercury and lead. For example, heavy metal accumulation increases the brain’s vulnerability to neurotoxic shocks through mechanisms such mitochondrial failure, calcium-ion dyshomeostasis in neurons and glia, an accumulation of damaged proteins, reduced DNA repair, decreased neurogenesis and impaired energy metabolism. Alongside causing cognitive deterioration and dysfunction of the autonomic nervous system, neurotoxicity has also been shown to be a major contributor to progressive neurological disorders such as Alzheimer’s and Parkinson’s diseases. This Special Issue will explore “New Insights into Neurotoxicity”, and how it influences the aging process and tips normal aging into a disease state, as well as new approaches to provide neuroprotection, neuroplasticity and neurorepair.
Dr. Paul L. Chazot
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- neurotoxicity
- neurotoxicants
- nervous system
- heavy metal
