Role of NLRP3 in Inflammation and Tumour
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (20 November 2023) | Viewed by 1179
Special Issue Editor
Special Issue Information
Dear Colleagues,
Investigations of various inflammatory mechanisms have pointed to a major role for inflammasomes which are multi-molecular complexes and potent inducers of immunity. Inflammasomes such as NLR Pyrin Domain Containing 3 (NLRP3), produce the inflammatory cytokines IL-1β and IL-18 and are implicated in both inflammation and cancer. Depending on the context of models and setting utilised, the role assigned for NLRP3 in both inflammation and cancer varies from pro to anti-inflammatory and from tumour suppression to tumour causation. The aim of this Special Issue is to bring about the latest thinking in terms of roles played by NLRP3 in health and disease with a particular focus on inflammation and cancer.
Dr. Rajaraman Eri
Guest Editor
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Keywords
- NLRP3
- inflammation
- inflammasomes
- tumour
