Special Issue "Enzyme Structure Function Stability"
Deadline for manuscript submissions: 30 December 2023 | Viewed by 10063
Interests: biocatalysis; biotechnology; medical biotechnology; bacteriophage-mediated biocontrol; glutathione biochemistry
Interests: protein structure function stability; enzyme biotechnology; protein bioinformatics; biochemical analysis and biotechniques; protein chemical modification; extremophilic enzymes
Proteins are central to all vital functions in biological systems. Enzymes are biocatalytic proteins that increase the rate of metabolic reactions to sustain life under environmental and physiological conditions. Due to their high substrate specificity and tremendous acceleration over non-catalysed reactions, enzymes have potential and real applications in the diverse fields of medical, industrial, agriculture and environmental biotechnologies. Enzymes also play key roles in aetiology of many diseases, which has led to an ever-expanding effort to identify efficacious inhibitors. In order to exploit their full potential, the sequence-structure-function-stability relationship of an enzyme needs to be comprehensively elucidated. This requires the development and application of novel cutting-edge technologies to study and resolve all aspects of enzyme kinetics.
In this special issue we will discuss current research on the structure-function-stability relationship in enzymes of medical, environmental and industrial importance. We are also interested in advanced tools such as cryo-electron microscopy for protein structure elucidation, ab initio protein structure prediction, single molecule enzymology, high-throughput microfluidic enzyme kinetics and any other novel methods that are topical and have potential to contribute towards understanding and optimizing structure-function in proteins. With the current on-going COVID-19 pandemic, articles on the viral enzymes are also welcomed. Due to industrial and environmental applications, topics dealing with the polyextremophilic enzymes are also solicited. Kindly note that as IJMS focus is on molecular science, pure clinical studies will not suitable. However, clinical submissions that involve the introduction and discussion of biomolecular mechanisms are welcome. We are open to all types of articles including research, review and opinion.
Dr. Wallace Bridge
Dr. Khawar Sohail Siddiqui
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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- enzyme structure
- enzyme function
- enzyme stability
- protein/enzyme analysis tools
- COVID-19 viral enzymes
- polyextremophilic enzymes
- enzyme biotechnology
- Ab initio protein structure prediction
- cryo-electron microscopy
- single molecule enzymology
- high-throughput microfluidic enzyme kinetics