Mitochondrial Footprint in Neurological Pathology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 April 2024 | Viewed by 870
Special Issue Editor
Interests: Alzheimer’s disease; mitochondria; brain tolerance; hypoxia
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurological disorder is an umbrella term for a range of brain and spinal cord diseases primarily characterized by progressive deterioration in the structure and/or functioning of neuronal cells. Neurological disorders encompass a variety of pathological conditions including (but not limited to) Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, ataxia, stroke, and epilepsy. Affecting hundreds of millions of people worldwide, neurological diseases are considered a leading cause of disability and the second leading cause of death worldwide. Despite their different symptomatology and pathological nature, most neurological disorders are accompanied by alterations in mitochondrial biology. Considered the “cell’s powerhouse”, mitochondria also fulfill several other physiological functions, such as modulation of ionic homeostasis, oxidation of carbohydrates and fatty acids, and regulation of cell death, making these organelles vital for proper neuronal functioning.
The Special Issue “Mitochondrial Footprint in Neurological Pathology” aims to provide a comprehensive and updated overview of the involvement of mitochondria in the pathological course of neurological disorders, and to highlight recent scientific breakthroughs on diagnostic biomarkers, pathophysiological mechanisms, and novel therapeutic interventions. That said, contributions from experts in the field in the form of original research or review articles are welcomed in this Special Issue.
Dr. Sónia Catarina Correia
Guest Editor
Manuscript Submission Information
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Keywords
- neurological disorders
- mitochondrial bioenergetics
- mitochondrial dynamics
- immunometabolism
- biomarkers
- mitochondrial medicine
