Cell Division: A Focus on Molecular Mechanisms
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 September 2024 | Viewed by 681
Special Issue Editors
Interests: cytokinesis; Golgi apparatus; membrane trafficking; cell cycle; cancer; Drosophila melanogaster
Special Issue Information
Dear Colleagues,
Cells divide and reproduce via two types of cell division processes: mitosis and meiosis. Mitosis, typical of somatic lineage, generates two identical daughter cells, while meiosis, which occurs in the germline, produces haploid gametes responsible for the transmission of genetic information to the next generation. Both processes require a highly regulated and carefully orchestrated sequence of events that induce remodeling of both the cytoskeleton and cell membranes. These changes ensure the formation of new cellular structures, such as the spindle apparatus necessary for correct chromosome segregation, and the disassembly/remodeling of pre-existing structures, such as the endoplasmic reticulum, Golgi apparatus and nuclear envelope later distributed and reformed in the cells that arise. Cytoplasmic material and smaller organelles, such as mitochondria, must also be distributed correctly within daughter cells. The failure of these mechanisms is the basis of numerous human pathologies such as cancer. Therefore, we welcome original papers and review articles to this Special Issue, with a focus on recent studies that disseminate greater knowledge of cell division and the molecular mechanisms that regulate this process to better understand its role in pathologies.
Dr. Stefano Sechi
Dr. Antonino Colanzi
Guest Editors
Manuscript Submission Information
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Keywords
- cell cycle
- cell division
- post-translational modification (PTM)
- mitosis/meiosis
- cell organelles
- cytokinesis
- membrane trafficking
- disease
- therapeutic target
- model organisms
