Functional Biocatalytic Molecules in Microbial Systems in Extreme Environments
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 30 May 2024 | Viewed by 1756
Special Issue Editor
Special Issue Information
Dear Colleagues,
Studies on extremophiles have resulted in the discovery of useful enzymes, with special characteristics and specific functions under specific or conventional conditions. Extremophiles are resources of useful enzymes or substances that work under desirable reaction conditions. There are several successful examples of biomolecules produced from isolated microorganisms. There are cases where the microbial communities in extreme environments exhibit biocatalytic functions. The microbial communities in extremophilic environments are highly sustainable and resilient when compared to those in the conventional systems employing single microorganisms. In addition, a series of reactions and interactions among different species of microorganisms could be utilized by using complexed microbial consortia. For advanced applications of such microbial ecosystem, it is necessary to elucidate the corresponding key molecular functions of the microbiota. These analyses will expand the discoveries of new functional molecules in extremophiles. Exploration should focus not only on functional molecules from the isolates but also on the genes in the microbial community. The biological systems and proteins in extremophiles undergo systematic changes in the metabolic system and structure, respectively, for survival under adverse physicochemical conditions. There are common features among such changes among the same category of extremophiles. We can understand that the distribution of such specific features in the bacterial genomes that are available in the database. The advent of new molecular biology tools and the acquisition of enormous genetic information in the database together with the development of bioinformatic methodologies has markedly changed the landscape for discovering and understanding ecological systems in the extreme environments as well as for biological systems in the cells of individual species in extremophiles during the last decade. This will enable a more comprehensive and systematic understanding of extremophiles and the knowledge could have wider future applications.
Prof. Dr. Isao Yumoto
Guest Editor
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Keywords
- microbial ecosystem
- functional molecules
- extremophile
- utilization of physicochemical conditions
- biocatalyst
