Synthesis, Activity and Mechanism of Enzyme Inhibitors
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 30 June 2024 | Viewed by 1324
Special Issue Editor
Interests: organic compounds; heterocycles; natural derivatives; biological activity; enzyme inhibition; anticancer activity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Enzymes are very effective biological catalysts that accelerate almost all metabolic reactions in living organisms. They are used as tools for studying enzymes and as well as for the design of new medicine drugs for treating certain disorders. Moreover, enzyme inhibitors and activators that modulate the velocity of enzymatic reactions play an important role in the regulation of metabolism. The suppression or activation of the enzyme activity is the result of the binding of inhibitor/activator to the enzyme molecule that arrests or accelerates catalytic reaction. Because enzymes catalyze most part of chemical reactions in living organisms, enzyme inhibitors play an important role in the development of different sciences (biochemistry, physiology, pharmacy, agriculture, ecology) as well as technologies (production of pharmaceutical drugs, insecticides, pesticides, chemical weapons, etc.). For this reason, there is growing interest in the search for new molecules as potential inhibitors or activators of various enzymes.
In this Special Issue, we welcome reviews, original research articles, and short communications that focus on advances related to the design, synthesis, and identification of new synthetic and natural enzyme inhibitors and their mechanism of action that can be used for the design of various types of pharmacological drugs and natural inhibitors as a plausible source for the design of future drugs.
Dr. Mariusz Mojzych
Guest Editor
Manuscript Submission Information
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Keywords
- organic compounds
- heterocycles
- enzymes inhibition
- mechanism of action
- natural products
- inhibitors
- interaction with enzyme
- kinetic studies of enzymatic reactions
