Cancer Immunotherapy: Tumor Microenvironment, Biomarker Discovery and Immune Resistance 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 10 August 2024 | Viewed by 1139
Special Issue Editor
Interests: rare cancers; lymphoma; biomarkers; translational research; genomics; spatial technologies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The field of cancer immunotherapy continues to excite basic scientific and translational research. From an oncologist’s perspective, immunotherapy has revolutionized contemporary cancer management, and is now considered a standard treatment option for many types of cancer. However, a major unmet need exists in that treatment resistance occurs in the vast majority of patients. A deeper understanding of tumor-intrinsic factors and their interplay with the tumor microenvironment has led to the identification of potential biomarkers of resistance and response, and has opened new avenues to improve upon existing treatment approaches. Moving forwards, it is anticipated that emerging innovative technologies that enable multi-dimensional, high-throughput and multiplex profiling will drive new discoveries in this aspect.
I cordially invite authors to submit original research and review articles to this Special Issue, which addresses the latest progress in and current understanding of complex mechanisms underlying responses and resistance to cancer immunotherapy.
In this Special Issue, experts in the field will review the latest research on the tumor microenvironment and its role in modulating immune resistance across various cancer types. Additionally, the topics will cover broad mechanisms of immunotherapy resistance and novel strategies to overcome them. It will also encourage research articles related to new predictive biomarkers and emerging therapeutic targets, as well as state-of-the-art technologies that accelerate studies in these areas.
Dr. Jason Yongsheng Chan
Guest Editor
Manuscript Submission Information
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Keywords
- cancer immunotherapy
- tumor microenvironment
- biomarkers
- immune resistance
- T cells
- immune checkpoint
- tumor-infiltrating lymphocytes
- tumor mutational burden
- dendritic cells
- PD-L1
