Special Issue "Molecular Biology and Therapeutic Properties of Mesenchymal Stromal Cells"
Deadline for manuscript submissions: 20 January 2024 | Viewed by 2522
Interests: functional biomaterials; drug delivery systems; 3D multicellular models; stem cell biology; cancer biology; cell engineering
Mesenchymal stromal cells (MSCs) are involved into regulation of stem cell niches in various tissues and play a pivotal role in tissue regeneration. In particular, MSCs are able to replenish stem cell pool at the site of injury via paracrine activity and exosome production. Moreover, MSCs significantly contribute to angiogenesis and extracellullar matrix production that provides mechanical support and nutrient supply to the cells in newly-formed tissue. Owing to the mentioned properties, MSCs and their derivatives have been used for numerous applications in regenerative medicine. It is believed that therapeutic effects of MSCs can be boosted via increase of survival rate and homing of the transplanted cells. It can be achieved due to different methods including chemical functionalization, pre-condition with biologically active molecules or genetic modification.
For this Special Issue, to be published in the International Journal of Molecular Science, researchers who are active in development of MSC-based therapies or in molecular mechanisms of therapeutic effects of MSC are invited to submit their latest results. Papers covering genetic and non-genetic modifications of MSC aiming at improvement of their regenerative properties, are also welcome.
Dr. Mikhail O. Durymanov
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- mesenchymal stromal cells
- regenerative medicine
- growth factor
- cell homing
- wound healing