Drug Discovery: Design, Synthesis and Activity Evaluation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 476
Special Issue Editors
Interests: heterocyclic compounds
Interests: organic chemistry; green synthetic organic chemistry; synthesis of heterocyclic compounds; natural products; NMR techniques; synthesis of new compounds with biocidal and antioxidant activities
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The Special Issue “Drug Discovery: Design, Synthesis and Activity Evaluation” aims at publishing studies within the medicinal chemistry field. In particular, it intends to cover the early stage of preclinical research in the drug discovery pipeline, including target identification and validation; hit discovery; assay development and screening; high-throughput screening; hit to lead; lead optimization; in vivo, in vitro and ex vivo assays; absorption, distribution, metabolism, and excretion (ADME); and drug delivery. Moreover, it welcomes not only original research papers, but also comprehensive reviews.
The original research papers should comprise the design (with or without computational support), organic synthesis, characterization, and biological activity evaluation of novel potent lead compounds, considering small to large biologically active molecules.
Dr. Joana L. C. Sousa
Prof. Dr. Artur M. S. Silva
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- drug design
- organic synthesis
- biological activity evaluation
- biologically active compounds
- diagnostic/therapeutic agents
- labeled ligands
- structure–activity relationships (SARs)
- structural biological studies
- computational studies
- pharmacokinetics/pharmacodynamics
- drug delivery
