Deciphering Allergies—Structural and Immunological Characterization of Allergenic Proteins and Immunomodulatory Agents
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 30 May 2024 | Viewed by 1322
Special Issue Editors
Interests: molecular allergology; immunology
Special Issue Information
Dear Colleagues,
Allergies are one of today's most common immune disorders; this is mostly because of an exaggerated immunoglobulin E-mediated immune response to harmless environmental allergens. The main translational goal to study allergies is to understand immune mechanisms, improve diagnosis, find a better and reliable immunotherapy, and manage the disease. Other factors, such as exposomes (parasites, ticks, drugs, heavy metals, plastic, and other contaminants) represent novel elements that act as important immunomodulatory agents in the allergic diseases and should be further investigated.
Therefore, the basis to achieve these goals are in the structural and immunological characterization of allergenic proteins; the interplay between allergens and innate and adaptive immunity; the development of novel therapeutic approaches; and the investigation of exposomes as immunomodulatory agents.
Potential topics include but are not limited to:
- Allergens: new and old epitopes enrolled in IgE binding and allergenicity;
- In silico discovery of allergens and prediction of allergenicity and allergic cross-reactivity;
- Allergenicity prediction of novel foods;
- Modulation of immune response by designed allergenic proteins;
- Allergen structure interplay with the innate immunity;
- Parasites and vectors as allergen transmitters;
- Effects of environmental pollutants on allergenicity;
- Effects of micro- and nano-plastics on protein allergenicity.
Dr. Marija Gavrović-Jankulović
Dr. Danijela Apostolović
Guest Editors
Manuscript Submission Information
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Keywords
-
allergen
- allergenicity
- IgE
- innate immunity
- exposome
- cross-reactivity
- B cell epitopes
- T cell epitopes
- in silico prediction
