Special Issue "Advances in Antimicrobial Nanomaterials 2.0"
Deadline for manuscript submissions: 15 December 2023 | Viewed by 1017
Interests: synthesis of metallic nanoparticles; nanofibers; antimicrobial activity; photodynamic therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue in International Journal of Molecular Sciences: Advances in Antimicrobial Nanomaterials
Special Issue in International Journal of Molecular Sciences: Biomaterials and Antimicrobial Materials for Orthopaedic Application
Special Issue in International Journal of Molecular Sciences: New Types of Antimicrobial Biocides
Special Issue in International Journal of Molecular Sciences: Biomaterials and Antimicrobial Materials for Orthopaedic Application 2.0
The problem of the presence of multidrug-resistant bacteria in the human environment has worsened the difficult clinical situation due to the reduced antimicrobial activity of known antibiotics. An example of such microbes is the group of pathogenic bacteria called ESKAPE. The acronym ESKAPE consists of the first letters of the generic names of the following bacteria: Enterococcus, Staphylococcus, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacteriaceae. This acronym covers bacterial pathogens that cannot be eliminated using classical antibiotics.
In addition, there is a growing concern regarding infections associated with the biofilm formation, which may be resistant to the currently available arsenal of antimicrobial agents. Therefore, there is an urgent need to develop alternative protocols for combating antimicrobial resistance to chemotherapeutic drugs.
Over the last two decades, there has been a significant increase in the use of nanodrugs as innovative tools to combat the antimicrobial resistance of pathogens. In this respect, nanomaterials have shown promise due to their unique physical and chemical properties. Their large surface in relation to the volume allows for close interaction with microbial membranes as well as their surface functionalization. Scientists are primarily interested in metal nanoparticles as innovative tools to combat pathogen resistance to conventional antimicrobial agents. The antimicrobial activity of several metals, metal oxides, metal halides, and bimetallic nanoparticles has been well documented. Moreover, the functionalization of nanoparticles using chemotherapeutic drugs is not only a promising nanoplatform for combating bacterial resistance but may also reduce the dose of the drug and, thus, its toxicity.
On the other hand, antimicrobial nanoparticles can be entrapped in polymer membranes to form hybrid nanoparticles or nanocomposites. It is also possible to improve the therapeutic efficacy of nanoparticles and reduce their toxicity by modifying the surface using ligands or antibodies.
We are interested in manuscripts that report new antimicrobial protocols related to various nano-sized materials but also provide reviews of the subject.
Prof. Dr. Irena Maliszewska
Manuscript Submission Information
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- metallic nanoparticles
- bimetallic nanoparticles
- antimicrobial activity
- polymeric nanomaterials
- nanoparticle functionalization
- delivery of antimicrobial agents