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Latest Review Papers in Molecular and Cellular Biology 2024

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 2310

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Dear Colleagues,

This Special Issue aims to collect high quality review papers in all the fields of Molecular Biology. We encourage researchers from related fields to contribute review papers highlighting the latest developments in Molecular Biology, or to invite relevant experts and colleagues to do so. Full length comprehensive reviews will be preferred.

Prof. Dr. Stefano Papa
Guest Editor

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Keywords

  • molecular biology
  • cell biology
  • signal transduction
  • macromolecules and complexes
  • gene expression
  • DNA structure, damage and repair
  • bioinformatics
  • imaging techniques

Published Papers (1 paper)

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Review

15 pages, 560 KiB  
Review
Essential Role of Astrocytes in Learning and Memory
by Paula Escalada, Amaia Ezkurdia, María Javier Ramírez and Maite Solas
Int. J. Mol. Sci. 2024, 25(3), 1899; https://doi.org/10.3390/ijms25031899 - 05 Feb 2024
Cited by 1 | Viewed by 2141
Abstract
One of the most biologically relevant functions of astrocytes within the CNS is the regulation of synaptic transmission, i.e., the physiological basis for information transmission between neurons. Changes in the strength of synaptic connections are indeed thought to be the cellular basis of [...] Read more.
One of the most biologically relevant functions of astrocytes within the CNS is the regulation of synaptic transmission, i.e., the physiological basis for information transmission between neurons. Changes in the strength of synaptic connections are indeed thought to be the cellular basis of learning and memory. Importantly, astrocytes have been demonstrated to tightly regulate these processes via the release of several gliotransmitters linked to astrocytic calcium activity as well as astrocyte–neuron metabolic coupling. Therefore, astrocytes seem to be integrators of and actors upon learning- and memory-relevant information. In this review, we focus on the role of astrocytes in learning and memory processes. We delineate the recognized inputs and outputs of astrocytes and explore the influence of manipulating astrocytes on behaviour across diverse learning paradigms. We conclude that astrocytes influence learning and memory in various manners. Appropriate astrocytic Ca2+ dynamics are being increasingly identified as central contributors to memory formation and retrieval. In addition, astrocytes regulate brain rhythms essential for cognition, and astrocyte–neuron metabolic cooperation is required for memory consolidation. Full article
(This article belongs to the Special Issue Latest Review Papers in Molecular and Cellular Biology 2024)
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