The Molecular and Cellular Mechanisms of Neurodegenerative Diseases 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 September 2024 | Viewed by 1731
Special Issue Editor
Interests: Alzheimer’s disease; frontotemporal lobar degeneration; traumatic brain injury
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases are a group of age-related complex diseases in the central nervous system including Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal lobar degeneration (FTLD), amyotrophic lateral sclerosis (ALS), Huntington’s disease (HD), and prion diseases. They are characterized by protein aggregates in particular cell types and brain regions, selective neuronal loss, neuroinflammation, progressive degeneration of the nervous system, and neurobehavior changes. Over the last decade, our understanding of neurodegenerative dieases has witnessed significant advances, especially at the molecular and cellular levels, although there are no effective therapeutics to prevent or halt these devastating diseases to date.
The goal of this Special Issue is to gain a better understanding of the cellular and molecular mechanisms in the pathogenesis of different neurodegenerative disorders, with a focus on protein homeostasis, unfolded protein response, synaptic dysfunction, neuroinflammation, alterations in brain metabolism, mitochondrial dysfunction, and oxidative stress mechanisms at the molecular and cellular levels.
We would like to invite you to submit original research articles and reviews that focus on, but are not limited to, innovative and important findings that provide a comprehensive view of the molecular mechanisms underlying the pathogenesis of neurodegenerative diseases. Studies involving transcriptomic, proteomic, and metabolomic approaches are encouraged.
Dr. Hongjun (Harry) Fu
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neurodegenerative diseases
- Alzheimer’s disease (AD)
- Parkinson’s disease (PD)
- frontotemporal lobar degeneration (FTLD)
- amyotrophic lateral sclerosis (ALS)
- Huntington’s disease (HD)
- prion diseases
- cellular and molecular mechanisms
- omics
