Toxicology of Xenobiotic Mixtures and Health
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601).
Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 26954
Special Issue Editors
Interests: pancreatic cancer; environmental toxicants; mitochondrial toxicity; apoptosis; cellular regulation; tryptophan-kynurenine pathway; indoleamine 2,3-dioxygenase
Special Issues, Collections and Topics in MDPI journals
2. Biomedical Engineering and Nano Technologies Institute, Riga Technical University, LV-1048 Riga, Latvia
3. Ghitu Institute of Electronics Engineering and Nanotechnologies, MD 2028 Chisinau, Moldova
Interests: sensing/detection; nanomaterials; security; defense; foresight; water; ecological chemistry; sustainability
Special Issues, Collections and Topics in MDPI journals
Interests: toxicology of mixtures; endocrine disrupting chemicals; human health risk assessment; chemical carcinogenicity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Today, society is exposed to hundreds of various agents in the form of particulate matter (nanoparticles), gases and vapors (air pollution), water pollution, multiple drugs and chemicals that have been either reported to be toxic or just suspected of being toxic (water pollution, food contamination, etc.). These confirmed or alleged toxicants can enter the body via inhalation of dust, ingestion of contaminated water, or consumption of foods or crops which are contaminated. The importance of the toxicological study of mixtures cannot be understated. Multiple scientific committees of the European Commission have concluded that understanding the toxicology of chemical mixtures is vital to human health. The Environmental Protection Agency and the Food and Drug Administration in the United States have echoed these sentiments, calling for increased funding and research on the toxicology of mixtures. Exposures to multiple chemicals, even at concentrations well below the toxic threshold for individual compounds, could have robust effects on health after long-term exposure. Major concerns linked to the exposure to multiple chemicals regard: a) Chemical interaction between agents that may alter the reported functioning of the individual chemicals, b) Combinations of agents that may cause effects classified as potentiating, additive, synergistic, or even antagonistic, leading to unforeseen health outcomes, and c) Mechanisms of action of different chemical classes, many of which are unknown, making the prediction of their health effects difficult if not impossible.
Over the last five years, there has been an increased interest in the toxicology of mixtures, as indicated by special editions on multiple environmental exposures and, more specifically, on their effects on children’s health. For this Special Issue on “Toxicology of Xenobiotic Mixtures and Health” in the International Journal of Environmental Research and Public Health, we are interested in broad-scope original research, case studies, and review articles examining the effect of xenobiotic mixtures (chemicals, drugs, environmental toxicants, etc.) on health. Submissions can focus on naturally occurring or man-made agents as long as the focus of the research report is the toxicology of combined mixture(s). The goal of this Special Issue is to compile a repository of current, diverse works investigating the various health effects associated with the exposure to combinations and mixtures of multiple agents.
Prof. David R. Wallace
Prof. Ashok Vaseashta
Assoc. Prof. Aleksandra Buha
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
