Stimuli-Responsive Hydrogel

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Analysis and Characterization".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 1471

Special Issue Editors


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Guest Editor
1. Department of Chemical Sciences, Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires CP 1113, Argentina
2. Institute of Chemistry and Drug Metabolism (IQUIMEFA-CONICET), University of Buenos Aires, Buenos Aires C1113AAD, Argentina
Interests: natural polymers; nanocomposites; smart hydrogels; strain sensors; characterization techniques

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Guest Editor
Department of Basic Sciences - CONICET, National University of Luján (UNLu), Luján 6700, Argentina
Interests: bioresourses; polymers; nanocomposites; stimuli responsive materials; hydrogel

Special Issue Information

Dear Colleagues,

The properties of stimuli-responsive hydrogels have attracted the interest of the scientific community, almost becoming a specific field within materials science. They have the ability to change their properties in the face of a stimulus, either to act on a target or to sense a change in the environment. This capability makes them interesting, for basic research as well as for their potential technological applications. The focus of these hydrogels has been mostly on medicine, but their field of application expands day by day.

The aim of this issue is to create a collection of articles based on all the aspects of stimuli-responsive hydrogels. Reports embracing novel synthetic routes, greener precursors, solvents and processes for known methods, e.g., the use of natural polymers, and interesting scalable or innovative strategies (such as 3D printing) for obtaining stimuli-responsive hydrogels are welcome. We are also interested in studies aimed at unraveling mechanisms of responses to stimulus and their characterization, in particular the ones related to (multi)responsiveness and/or nanoparticle-enhanced response. Finally, we encourage reports that deal with feasible technological developments with real applicability and the production of these materials as part of a circular economy.

We look forward to receiving your contributions.

Dr. Guillermo Javier Copello
Dr. María Emilia Villanueva
Guest Editors

Manuscript Submission Information

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Keywords

  • hydrogels
  • stimuli-responsive
  • synthetic routes
  • material characterization
  • technological applicability

Published Papers (1 paper)

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Research

18 pages, 3952 KiB  
Article
Polysaccharide-Based Hydrogel from Seeds of Artemisia vulgaris: Extraction Optimization by Box–Behnken Design, pH-Responsiveness, and Sustained Drug Release
by Muhammad Ajaz Hussain, Arshad Ali, Tariq G. Alsahli, Nadia Khan, Ahsan Sharif, Muhammad Tahir Haseeb, Omar Awad Alsaidan, Muhammad Tayyab and Syed Nasir Abbas Bukhari
Gels 2023, 9(7), 525; https://doi.org/10.3390/gels9070525 - 28 Jun 2023
Cited by 1 | Viewed by 1260
Abstract
The current research work focuses on the extraction and optimization of the hydrogel (AVM) from the seeds of Artemisia vulgaris using Box–Behnken design-response surface methodology (BBD-RSM). The AVM was obtained through a hot water extraction process. The influence of different factors, including pH [...] Read more.
The current research work focuses on the extraction and optimization of the hydrogel (AVM) from the seeds of Artemisia vulgaris using Box–Behnken design-response surface methodology (BBD-RSM). The AVM was obtained through a hot water extraction process. The influence of different factors, including pH (U = 4 to 10), temperature (V = 25 to 110 °C), seed/water ratio, i.e., S/W ratio (W = 1/10 to 1/70 w/v), and seed/water contact time, i.e., S/W time (X = 1 to 12 h) on the yield of AVM was evaluated. The p-value for the analysis of variance (ANOVA) was found to be <0.001, indicating that the yield of AVM mainly depended on the abovementioned factors. The highest yield of AVM, i.e., 15.86%, was found at a pH of 7.12, temperature of 80.04 °C, S/W ratio of 1/33.24 w/v, and S/W time of 8.73 h according to Design-Expert Software. The study of the pH-responsive behavior of AVM in tablet form (formulation AVT3) revealed that AVM is a pH-responsive material with significantly high swelling at pH 7.4. However, less swelling was witnessed at pH 1.2. Moreover, AVM was found to be a sustained release material for esomeprazole at pH 7.4 for 12 h. The drug release from AVT3 was according to the super case-II transport mechanism and zero-order kinetics. Full article
(This article belongs to the Special Issue Stimuli-Responsive Hydrogel)
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