Mitochondrial Metabolism in Skeletal Muscle
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 August 2024 | Viewed by 128
Special Issue Editor
Interests: aging; stroke; skeletal muscle atrophy, growth, regeneration, and metabolism; genomics; proteomics; metabolomics; bioinformatics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Skeletal muscles are composed of long, cylindrical cells called muscle fibers. These fibers are bundled together to form muscles that are directly connected to bones, allowing for voluntary movement. In order to function effectively, skeletal muscles require a constant supply of energy to meet the demands of physical activity. This is where mitochondria come into play. Mitochondria are often referred to as the "powerhouses" of the cell due to their ability to produce ATP through oxidative phosphorylation. While ATP can be generated through other pathways, the majority of the ATP in skeletal muscles is produced within the mitochondria. Additionally, the number of mitochondria within skeletal muscle fibers can adapt and change in response to physical activity levels. Endurance exercise training, such as long-distance running or cycling, has been shown to increase skeletal muscle mitochondrial biogenesis, which will improve their capacity to generate ATP and enhance overall muscle endurance. Skeletal muscle mitochondria also play a vital role in buffering calcium ions within muscle cells. Calcium ions are essential for muscle contraction. Mitochondria have been shown to efficiently sequester and store excess calcium ions, acting as a protective mechanism for muscle fibers. This Special Issue covers topics related to any mitochondrial work of muscle tissues from any animal models (invertebrates and vertebrates). Authors interested in contributing their research findings to this Special Issue are invited to provide a tentative title and authorship to the Guest Editor. Manuscripts will be peer reviewed following the standard journal procedures.
Dr. Junaith S. Mohamed
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- skeletal muscle
- mitochondria
- mitochondrial dysfunction
- mitochondrial diseases
- mitochondrial biogenesis
