Intracellular Mechanism in Differentiation, Proliferation and Cell Death

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".

Deadline for manuscript submissions: 1 November 2024 | Viewed by 284

Special Issue Editors

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Guest Editor
Institute of Convergence Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans University, 1071 Anyanycheon-ro, Yangcheon-gu, Seoul 07985, Republic of Korea
Interests: mesenchymal stem cells; regenerative medicine; epigenetics; immunotoxicology; immunomodulation; inflammation
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Molecular Medicine, College of Medicine, Ewha Womans University, 25 Magokdong-ro-2-gil, Gangseo-gu, Seoul 07804, Republic of Korea
Interests: regenerative medicine; mesenchymal stem cells; differentiation factors; signaling pathway; nitric oxide; far-infrared radiation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cells have their own unique as well as pleiotropic roles to perform in numerous biological activities to assist in maintaining biological homeostasis. All these processes are achieved through the complex internal and external interaction of molecular signals. The internal maneuvers are crucial for the cells to adapt in response to external cues and, as a consequence, understanding these underlying intracellular mechanisms is important for studying cells. General cellular processes, including proliferation, differentiation and cell death (apoptosis versus necrosis), are the most commonly assessed endpoints in evaluating the medicinal or toxic effects of chemical, biological and any other external factors. Many studies have been performed in relation to these biological processes, yet their underlying mechanisms have not yet been fully understood due to the complexity of the regulatory mechanisms involved. There are still many intracellular mechanisms to discover in the diverse field of cell biology such as immunology, neurology, toxicology, regenerative medicine and so on. For example, stem cells are capable of self-renewal until undergoing an epigenomic arrangement or differentiation to become functional adult cells. However, it is still difficult to control their proliferation and differentiation due to uncertainty in their intracellular regulatory mechanisms, making their application difficult in clinical field.

This special issue aims to extend knowledge on the complex intracellular regulatory mechanisms of differentiation, proliferation and cell death in the hope of forging safe and effective treatments for various pathological conditions.

Dr. Steve (Se-Young) Oh
Prof. Dr. Inho Jo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • intracellular mechanism
  • molecular pathway
  • differentiation
  • proliferation
  • cell death
  • apoptosis
  • necrosis
  • inflammation
  • epigenomics
  • proteomics

Published Papers

This special issue is now open for submission.
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