Pathophysiological Mechanisms of Cholestatic and Metabolic-Associated Fatty Liver Disease
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 140
Special Issue Editor
Interests: liver physiology; chronic liver diseases; toxicology; functional imaging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic-associated fatty liver disease (MAFLD) and cholestatic liver diseases represent a major health problem. Interestingly, both disease groups share some key mechanisms that can be therapeutically addressed, including specific nuclear receptors controlling glucose, lipid and bile acid homeostasis, immune cell infiltration, fibrosis, proliferation and the compromise of transport processes. The Special Issue will focus on pathomechanisms and/or therapeutic interventions in cell systems, animal models or in patients. In this Special Issue, an overview about the currently available knowledge and recent findings regarding the development, progression, molecular pathways, and mechanisms of these diseases is given.
Prof. Dr. Jan G. Hengstler
Guest Editor
Manuscript Submission Information
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Keywords
- steatosis
- steatohepatitis
- bile flux
- inflammation
- FXR
